Protein Alignment SP1029 and AC3.5

DIOPT Version :9

• Sequence 1: NP_001263065.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_001256214.1
• Gene: AC3.5 / 179447
• WormBaseID: WBGene00007071
• Length: 1090
• Species: Caenorhabditis elegans
• Alignment Length: 1030
• Identity: 225/1030 - (21%)
• Similarity: 412/1030 - (40%)
• Gaps: 224/1030 - (21%)

  Fly    18 ADSSADSIETTYNYYRLPTSLRPQKY-----------------HLRI------LTLLENPEDLRF 59
            ||.:|...:.|.....||.:::|..|                 |:::      ..::.|.:|:.|
 Worm   140 ADENASIKQPTKEELALPKNVQPVWYDVSLSPKVGGNGTMGLAHVKLNIEEPTNKIVLNAKDIEF 204

  Fly    60 SGSVKILIEALENTKNVTLHSKNLTIDESQITLRQIGGEGKKENCVSSTA-------VNPSHDF- 116
            :.:    :|.::.:|.||..:|. ::|....:..:: .||..|..:::||       ..|...|
 Worm   205 TRN----LEKIQLSKEVTKRAKK-SVDSGTNSTSEM-PEGSGEEAMATTATTTTTESTTPVSSFV 263

  Fly   117 -----------------YILNTCQELLAGNTYELYMPFAADL--NRQLEGY-YRSSYKDPVANLT 161
                             ..|...|||..|:|..|.:||.:.:  |..|:.| |::|.....:..|
 Worm   264 DTGIKVTNIEFDENLEKVTLTLDQELKKGSTVVLKIPFTSKVSNNNGLKEYKYKNSEGKEQSMFT 328

  Fly   162 KWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETK-------------- 212
                 ||...:..|..||.||:..||||..:||.:.|....::|...| ||
 Worm   329 -----TQPSYSYLRHVFPSFDQEAFKAPAAITLMHSKGSIVVANTGVK-TKDDGDAQTSTLNKVL 387

  Fly   213 -PHETLADYIWCEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARPNAIDQCDYAAQFGP 276
             |...:.|               |||..||..|        ....|.|.||......:.:..:..
 Worm   388 DPDFVIGD---------------LVASEVNTTS--------GITIRIWTRPEVKHSTEQSLDYAN 429

  Fly   277 KVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQRVASVVA 341
            :.:...|.....:.....:|.:|||.|..|...:...:...|..:||:...:.:..|.|:|.:::
 Worm   430 QAIDAMEHILQSRLESKSLDIVAVPGFQTGNRVSPSFIVLPEEDILYNEQSNDINQKTRIARMIS 494

  Fly   342 HELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVE---NINPE--WRSMEQESLSNLLTIFRRD 401
            :.:|.||||.:...:.:...||||....::....:|   :||.:  | :.|.|.      |..||
 Worm   495 NRIAAQWFGGITNPEEFGTFWLNEALPRFLEVEALEKILDINSDDLW-TYEMEK------ILERD 552

  Fly   402 ALESSHPIS-RPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNA-- 463
            |..:|.|:. :.:...::|:|...:...:||:.||||:...:|...|...:::::.  ||::|
 Worm   553 ATATSQPLRVKNVFSSADIAEIDHEFIGKKGAAVLRMIQKSVGVNVFNKAIRSFVS--SYRSAYP 615

  Fly   464 EQDNLWESLTQA----AHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLL 524
            ..|.||:|..:|    ...:.:.|  .|:...:::|..|.|:|:::|.: ....|.:|:|||:..
 Worm   616 YDDGLWKSFEKALGGKLKGWNNEP--LDVAKFVNTWVDQIGFPLVSVEK-LDDETVELSQERFKN 677

  Fly   525 N--TQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGE--------SLPKTIQDLPGP 579
            :  |:....:|...:|            ||...|......|..|.        .||....|.
 Worm   678 DHKTKEQFKFRNAKYW------------FNWEVPLFLKSSGPVGNVSWLHEAFRLPLNTSDS--- 727

  Fly   580 DQWVIFNTQLSTLYKVNYDAQNWKLLIETL--TNGDF-ERIHVINRAQLIDDALYLAWTGEQDYE 641
               :..||..:.:|:|||:.:.|..:.:.|  ::|.. ||    .||:||.|...||.:|...:|
 Worm   728 ---IYLNTDSNGVYRVNYEEKRWNDIAKQLEKSHGKLSER----TRARLISDVFALANSGALPFE 785

  Fly   642 IAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLN-------- 698
            .|:.:..||..|...:||..|....|::...:...|..:....::.:.|...:|.::
 Worm   786 TALNVTSYLPMETATVPWLIATRIFKKLTERLEGAPIQDKLNSFIYQKIHKKFEEISSSPGEASS 850

  Fly   699 ---------GINDTFSAI-PQQDQVLLKTMVVNW---ACQYQ---VGDCVPQALAYYRNWRAEAN 747
                     .:.|..:.: |::....|..:.|..   .||:.   ..||
 Worm   851 NYLKNRLYANLLDLMAIVKPEKSNEKLNELFVEGFLAPCQFSGNFSSDC---------------- 899

  Fly   748 PDEKNPVPINVRSTVYCTSIKHGSDSDWEFLWTRYKKSNVAAEKRTILTALGCSREVWLLQRY-- 810
                :.||.::|..|||..::.|:|:.:|.:....:|....|||..:..:|.|.|:...|:|.
 Worm   900 ----SEVPGDLREKVYCNGVEFGNDTVFETVRELAEKEVDGAEKDLLQNSLACFRDPRALRRLIL 960

  Fly   811 --LELTFDPKEAIRKQDSMWAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLS 873
              |..|......:||.:|         ..||..:|..:.:||...:.|   ...|:....|:.::
 Worm   961 DNLNSTSTVTLLLRKMNS---------RPVGKEIATNWIIDNWSTVLK---KKFKNDPETLNAIA 1013

  Fly   874 EQVITLSDFNE---FKDFVNNSRQSLKGLEQAIQQTLEIMLTNVQWKERNYHQMS 925
            :..|.|.:..|   .:.|:.:..:|..|:| ::.:.:|...|::.|:::..::::
 Worm  1014 DAGIILDNEREKSMIETFMEHHHKSTHGIE-SLDKKIEEATTDIYWRKQKINELN 1067

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_001263065.1	Peptidase_M1	33..431	CDD:279741	102/469 (22%)
		M1_APN_2	43..502	CDD:189008	120/536 (22%)
		ERAP1_C	583..908	CDD:288671	77/358 (22%)
AC3.5	NP_001256214.1	Peptidase_M1	156..574	CDD:279741	101/459 (22%)
		GluZincin	165..656	CDD:301352	120/536 (22%)
		ERAP1_C	728..1052	CDD:288671	78/360 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	110	1.000	Domainoid score	I3949
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020