Protein Alignment SP1029 and Y67D8C.9

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_001122826.1
• Gene: Y67D8C.9 / 177088
• WormBaseID: WBGene00022073
• Length: 1144
• Species: Caenorhabditis elegans
• Alignment Length: 1061
• Identity: 248/1061 - (23%)
• Similarity: 416/1061 - (39%)
• Gaps: 267/1061 - (25%)

  Fly    12 GLGLATADSS--ADSIETTYNYYRLPTSLRPQKYHLRILTLLENPEDLRFSG-SVKILIEALENT 73
            |.|:|....:  |:.:.|......||..:.|..|.|:          |.||. ...:.|.|
 Worm   158 GFGIAEQLHAVRANKLSTDALLVPLPLYILPYHYDLQ----------LDFSQFDTHLFIRA---- 208

  Fly    74 KNVTLHSK---NLTIDESQITL--------RQIGGEGKKENCVSSTAVNPSHDFYILN------- 120
             |:::|.:   |.|.||.|..|        .::..:|||              ||...
 Worm   209 -NISIHLESYGNSTEDEIQFHLGPNIKMERMRLRKDGKK--------------FYAKTFKREESK 258

  Fly   121 -----TCQELLAGNTYELYMPFAADL-NRQLEGYYRSSYKDPVANLTKWISVTQFEPASARLAFP 179
                 :.::.|....|.|.|.:...: :..::|...|......::|......|:|||..||..||
 Worm   259 KLGRISLRDPLQKGKYILEMTYNMTICDEDVDGVRCSLDNQTNSSLKATSFTTKFEPTLARAFFP 323

  Fly   180 CFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLAD-YIWCEFQESVPMSTYLVAYSVNDF 243
            |:|||..||.|.:::.::||||.:||||..|:..|::..| :....||.:.||||||:|:::.:|
 Worm   324 CWDEPGVKATFNISVRHNKKYTVLSNMPPVESHDHKSWEDQFKTTVFQTTPPMSTYLLAFAIGEF 388

  Fly   244 SHKPSTLPNSALFRTWARPNAIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAM 308
            ....|..........|..|..:....:..::.|.:....|....|.:||||:|.||..:|..|.|
 Worm   389 VKLESRTERGIPVTVWTYPEDVMSMKFTLEYAPVIFDRLEDALEIPYPLPKVDLIAARNFHVGGM 453

  Fly   309 ENWGLVTYREIALLYSAAHSS--------LADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNE 365
            ||||||.:...::.|:...:.        :.::.|:..::|||.|||||||||||:.|::|:|||
 Worm   454 ENWGLVVFEFASIAYTPPITDHVNETVDRMYNEFRIGKLIAHEAAHQWFGNLVTMRDWSELFLNE 518

  Fly   366 GFATYVASLGVENINPEWRSME-QESLSNLLTIFRRDALESSHPIS--RPIQMVSEISESFDQIS 427
            ||||:.....:....|.....| .:||::|:..    ..|..|.:|  |.:...|::..||...:
 Worm   519 GFATFYVYEMMSTERPVTAQFEYYDSLASLILA----QSEEDHRLSLVRELATESQVESSFHPTN 579

  Fly   428 -YQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSI 491
             |.||..::||:...:.:..|::.::.||:|.:|::..:|:|:.||...|.......|   :..:
 Worm   580 LYTKGCVLIRMLRDLVSDFDFKAAVRRYLRKNAYRSVSRDDLFASLPAYADHGAEQEK---LSHV 641

  Fly   492 MDSWTLQTGYPVINVTRDYAARTAKLNQE-------RYLLNTQVARA---YRGG----------- 535
            ::.|.:..|.|.|.:.|:|......::|.       |..|..:.|.|   |||.
 Worm   642 LEGWFVNEGIPEITLIRNYDNEMMTISQRKTVHHEYRSFLKDRKASASVRYRGSRSAEDGSTLFD 706

  Fly   536 ---------------------------------------------------CWWVPLSY------ 543
                                                               .|.:|::|
 Worm   707 DALFDGYIEKKKDRRRKHRPIRRKTSTPPSISPISRRDELRKPRRVGASQDLWTIPITYMFGSLK 771

  Fly   544 --TTQAVQDFNNTAPKAWMECGKNGESLPKTIQ--DLP-GPDQWVIFNTQLSTLYKVNYDAQNWK 603
              ..|.:::|       |:   ||     :|:.  |.. .|:|.|:.|.:....|:||||..|||
 Worm   772 TSEGQVIREF-------WL---KN-----RTVSFGDAEISPNQAVLVNPEWKYPYRVNYDLLNWK 821

  Fly   604 LLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLPWKSAFENLKR 668
            ||..||.....| |:..:|.|||.||.|.. :...:..:.:.|:.||..|.:........:.:.:
 Worm   822 LLARTLHQNHLE-INEKSRMQLILDAEYFL-SNSVNPHLYLYLLGYLAHETKMEVMLFGIDAVYK 884

  Fly   669 VGRIVRQTPDFEFFKRYMKKLILPIYEHLNGINDTFSAIPQQDQVLLKTMV-VNWACQYQVGDCV 732
            ...:.:.|        .:.|.||..:|         ..|.|.|.:|.::.| ...|..:.|.
 Worm   885 FIDVYKAT--------QLNKAILVYFE---------PVISQMDHLLNESQVDAETASLWLVR--- 929

  Fly   733 PQALA------------------YYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSD----W 775
            |:.||                  |.:.|  ..:|||... .::.:.|..|..:...:..:    .
 Worm   930 PERLAKLYQMRCAAGLSSCKNDYYTQRW--SRSPDEWTE-DVHKQVTAVCHQLFTNTPDEVKTVQ 991

  Fly   776 EFLWTRYKKSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEVGF 840
            :.|.:|.:.|  .|:....:....||.:..||:|........|.|:....::.:..::.:|..
 Worm   992 DLLDSRLQSS--GAKWALTVQLAACSHDQKLLRRTARAIVSTKNAVVYASALQSDFSLHYNPT-- 1052

  Fly   841 LLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSR----------QS 895
              .:||                         |..::..:|.|.:...|..||.          .|
 Worm  1053 --FRKY-------------------------LWAEIAKMSTFEKTALFSTNSTDILPASRILLHS 1090

  Fly   896 LKGLEQAIQQTLEIMLTNVQW 916
            :|.:::.  |.:..:|||  |
 Worm  1091 VKTIDEL--QQIRGLLTN--W 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	139/492 (28%)
		ERAP1_C	582..910	CDD:463368	72/360 (20%)
Y67D8C.9	NP_001122826.1	M1_APN-Q_like	190..645	CDD:341064	138/490 (28%)