Protein Alignment SP1029 and Y53F4B.20

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_497105.3
• Gene: Y53F4B.20 / 175160
• WormBaseID: WBGene00013166
• Length: 694
• Species: Caenorhabditis elegans
• Alignment Length: 704
• Identity: 143/704 - (20%)
• Similarity: 249/704 - (35%)
• Gaps: 186/704 - (26%)

  Fly     3 WFLLFVAALGLGLATAD-SSADSIETTYNYYRLPTSLRPQKYHLRI---LTLLENPEDLRFSG-- 61
            |.||::    .|:.|:| ....|....|:..|||..|:|..|.|::   |:.:.:|:...|:|
 Worm     4 WLLLYL----FGIVTSDLHQLLSTRPLYSDDRLPPILKPLSYDLQLQLPLSEVSDPDVPLFTGRC 64

  Fly    62 -------------------------SVKILIEALENTKNVTL--HSKNLTIDESQITLRQIGGEG 99
                                     .:|..|..|::.:||:|  :...|.|...|:|
 Worm    65 VMHFEINQQIGPESAFISDSTSNRARIKFDIIMLDHFENVSLVMNGHELEIFNVQLT-------- 121

  Fly   100 KKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQLEG------YYRSSYKDPV- 157
                          .|...|:..|.:|....|.|.:       .:.:|      |||.:.:..|
 Worm   122 --------------DDSMELSVDQPVLFPGRYTLTI-------HRYKGLIGSAIYYRDAGEHAVF 165

  Fly   158 -ANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLADYI 221
             :||.         |..|...||.:.....|..|.:|: .|...|........|..|.
 Worm   166 GSNLF---------PNRAPAVFPSYLASTEKVTFSITM-VHPVGTLALTSGSNEGAPR------- 213

  Fly   222 WCEFQESVPMSTYLVAYSV-----------NDFSHKPSTLPNSAL------FRTWARPNAIDQCD 269
              :..|:..|:|:....|:           ::::|..||.....:      ||...     :|..
 Worm   214 --KIDENWQMTTFSTTPSITPSMLCFLLLPHEYTHIESTYTGVNISVHYNRFRVQK-----EQTK 271

  Fly   270 YAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQ 334
            :......:||...:..|....|:||||.|.:.:.|:.|.  :|.:...|:...       .||..
 Worm   272 HLLHTATQVLALLKDIFSSLIPVPKIDIITMNEVSSTAC--FGSIVVSEVQFF-------SADYA 327

  Fly   335 RVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFR 399
            ....::|..||.||.|....:...::|.|.|....::|...::.:..:    |...|.:|..|:.
 Worm   328 NQVKMLATWLAKQWIGGYAAISEGSELCLQEDLVAFIADKVIKRMTND----EFTRLGHLAKIYL 388

  Fly   400 RDALESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYL---QKFSYK 461
            .:.:.::....:..:..:|. |.|::... ||..:|..:...:||:|..|.:...:   :|.||.
 Worm   389 SETIFTAGDTLKLDEHPNEF-EIFEKCGL-KGVAMLESIESLIGEKSMISKINEMIYNSKKGSYS 451

  Fly   462 NAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNT 526
            :.....|..|         ::.:...:..::..|....|.|.:||  |..|.:.|:.|.    .:
 Worm   452 SRTLYGLLNS---------TVDEDIYVSQLLHYWHEHGGLPYMNV--DRLANSIKITQN----GS 501

  Fly   527 QVARAYRGGCW-----W-VPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDL--------P 577
            .:......|.|     | :||.:|     :|                .||  ||.:        |
 Worm   502 NMTVKNGAGTWERMPLWPLPLKFT-----EF----------------KLP--IQIMVSHGIHLSP 543

  Fly   578 GPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALY 631
            ..|..:..|...:..|:||||...|: .|:|:...:.....:..|.||:.|..|
 Worm   544 IRDGLIFSNLGFTNYYRVNYDIDTWR-EIKTVLTENATSYTLRERFQLVSDFCY 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	95/514 (18%)
		ERAP1_C	582..910	CDD:463368	14/50 (28%)
Y53F4B.20	NP_497105.3	GluZincin	39..>300	CDD:472708	58/313 (19%)
		ERAP1_C	552..>593	CDD:463368	12/41 (29%)