Protein Alignment SP1029 and LOC1278754

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_318379.6
• Gene: LOC1278754 / 1278754
• VectorBaseID: AGAMI1_000623
• Length: 880
• Species: Anopheles gambiae
• Alignment Length: 955
• Identity: 246/955 - (25%)
• Similarity: 394/955 - (41%)
• Gaps: 164/955 - (17%)

  Fly    33 RLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNLTIDESQITLRQIGG 97
            ||..:..|..|.|.:........|..:.|:|.|.|..:.:|..|.||  |:......|.||:
Mosquito    26 RLSNNTLPLHYDLHLEATGLGLHDYTYRGNVSIRIAIVSDTNEVVLH--NVGNRLKSICLRR--- 85

  Fly    98 EGKKENCVSSTAVNPSHDFYILNTCQELLAGNT-----------YELYMPFAADLNRQLEGYYRS 151
                  |....|:  ||.........|||...|           ..|.:.|...|.....|:||:
Mosquito    86 ------CRDGEAI--SHQLLESEPASELLRIRTDRILRRADDQVITLTIVFHNTLGEDRMGFYRT 142

  Fly   152 SYKD----PVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETK 212
            .|:.    |:|     ::.|.|:|:.|||||||||||.||..|.:|:..:..:...||.|
Mosquito   143 QYRGAKRIPMA-----VATTHFQPSYARLAFPCFDEPGFKTTFQITIVANGSHLVASNAP----- 197

  Fly   213 PHETLADYIWCE-------FQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARPNAIDQCDY 270
                :|...|.:       |:.:.||.||||.:.:.:|:...:..|:.......|.|.......:
Mosquito   198 ----IATVTWLQDGHKAVRFERTPPMQTYLVTFLIANFTSVHTVSPSGVEIGILAPPKDEKSLQF 258

  Fly   271 AAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQR 335
            :.|....:|...|::.|....|.|:|.:|:|.| ..||||||||.|.|..|:.||....|...|.
Mosquito   259 SLQAATTLLSSLEEYTGQSLGLQKLDHVAIPRF-GNAMENWGLVAYDEQFLVLSAKAHRLQRAQA 322

  Fly   336 VASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQE-SLSNLLTIFR 399
            |.: :.||.|||.|||||...||:.|||:||||||...|...:..||...:|:. ::.::.....
Mosquito   323 VLT-IGHETAHQLFGNLVGPAWWSYLWLSEGFATYFELLLGADAYPELLPLEESFAVRHMHPALM 386

  Fly   400 RDALESSHPIS-RPIQM-VSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKN 462
            .||.| .||:: .|:.. ..||...||.|:|.|...:|||::..:|||:|::|:|.||::.....
Mosquito   387 ADAYE-QHPLTVEPLSANTPEIETLFDTITYSKAGCILRMINCSIGEEAFQAGVQNYLEQHRNGI 450

  Fly   463 AEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQ 527
            ...::|:.|......|     .:..::.:..||..:.||||:.|.| ......:..|:|| .|.:
Mosquito   451 VTPEDLYASFFVQQRK-----DTPTVEQMFRSWVDKPGYPVVTVER-LNGSFVRFRQQRY-HNQE 508

  Fly   528 VARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDL-----PGPDQWVIFNT 587
            |........|::|::|.|.:........|..||:         :|.|:|     ......::.|.
Mosquito   509 VTIQDITSRWFIPITYYTNSSLGQYEYQPAFWMK---------ETDQELVLQLKMNTQDVLVVNP 564

  Fly   588 QLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQR 652
            :....|:|.||.:.|..:::.||.     :..|.:|:|||||..||..|...||:.:.:::.|..
Mosquito   565 RQIGFYRVEYDERGWSSIVDNLTT-----LPSIMQAKLIDDAFVLARAGLVGYELCLEMLQELAT 624

  Fly   653 EREYLPWKSAF--ENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNG-INDTFSAIPQQDQVL 714
            ..:.:||..|.  ||:..:.|:: |:.:|:.|              |.| :.:.|.......:.|
Mosquito   625 SPDPVPWLIAMAEENIGYLQRVL-QSAEFDRF--------------LTGFVGEMFDLAGNVGRTL 674

  Fly   715 LKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSDWEFLW 779
            |::..::.|.     |...:..|.:...:.|::...:..:|..|:..|  .::....|...|.|:
Mosquito   675 LQSQALDVAY-----DWWSRLAASFIESKRESSIRPRACLPTPVQEVV--QALVSPDDHVRERLF 732

  Fly   780 TRY----KKSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQD-------SMWAFQAV 833
            .|.    |:||   |...:|.||...|...||..  ...|...|::.|.|       |:....:|
Mosquito   733 VRLKCLPKQSN---EPSVLLLALERIRAANLLTP--GKLFAVLESLIKSDPGRFLPPSVQFLSSV 792

  Fly   834 AFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQSLKG 898
            ...|.|                    |:.....|||:.:..:|.......:.:..:..:...|..
Mosquito   793 PPEEAG--------------------PVADRFQRLLNLIVHEVTDRRQAAQVRKLMVKNSSILPA 837

  Fly   899 LEQAIQQTLEIMLTNVQWK--------------------ERNYHQ 923
              ..:.....:|.:.:.|:                    ||..||
Mosquito   838 --NFLPHASTVMTSTISWRMKQVPKLREFVHDSHMASIYEREGHQ 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	146/479 (30%)
		ERAP1_C	582..910	CDD:463368	70/341 (21%)
LOC1278754	XP_318379.6	None