Protein Alignment SP1029 and LOC1275101

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_314331.5
• Gene: LOC1275101 / 1275101
• VectorBaseID: AGAMI1_000111
• Length: 915
• Species: Anopheles gambiae
• Alignment Length: 941
• Identity: 270/941 - (28%)
• Similarity: 446/941 - (47%)
• Gaps: 108/941 - (11%)

  Fly    29 YNYYRLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNLTIDESQITLR 93
            ::.||||.:..|..|.||:.|.:.. |...::|:|:|.|..||.|..:.|||     ..|:||..
Mosquito    36 FDSYRLPNTTVPTHYTLRLDTDIHR-EIFDYTGNVQIRINVLEATDQIVLHS-----SRSEITHV 94

  Fly    94 QI-GGEGKKENCVSSTAVNPSHDFYILNTCQELLAG-NTYELYMPFAADLNRQLE-GYYRSSYKD 155
            |: .|.|.... |.:...:...:|.::|....|... .||.|.:.|...:.|..: |:|||||.|
Mosquito    95 QLRNGVGLSVP-VKNFEFDEDKEFLVVNVGTTLQPNTGTYTLEIDFTNSIARNDQAGFYRSSYDD 158

  Fly   156 PVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKET------KPH 214
            . ..:.:::.:||||...||.:|||:|||..|..:.:.:.....|.|.||.|.:..      |..
Mosquito   159 E-NGVRRYLGLTQFESVDARTSFPCYDEPGIKTTYDILIVCGIDYHARSNAPLRGIQLLEGGKKL 222

  Fly   215 ETLADYIWCEFQESVP-MSTYLVAYSVNDFSHKPSTLPNSAL-FRTWARPNAIDQCDYAAQFGPK 277
            .|.|         :.| |.|||||:.|:||.::...|.:..| ..:|::|:::....|:.....:
Mosquito   223 STFA---------TTPRMQTYLVAWLVSDFKYEREVLTDPQLAIASWSKPSSVHLLSYSVDASKR 278

  Fly   278 VLQYYEQFFGIKFPLPKIDQIAV--PDFSAGAMENWGLVTYREIALLYSAAHSSLADKQR---VA 337
            .::..|::|...:.:.|||.:|:  .|::||||||||||||:|.|:.|.....    :||   |.
Mosquito   279 FMRAMEEYFDQLYSMSKIDNVAIKDEDYAAGAMENWGLVTYKESAISYGPEDG----EQRQVGVV 339

  Fly   338 SVVAHELAHQWFGNLVTMKWWTDLWLNEGFA-TYVASLGVENINPEWRSMEQESLSNLLTIFRRD 401
            ::|.||..||:||||:..|||:.|||||||| .|...||..: :||.:..|:.......|..|.|
Mosquito   340 TIVGHEFTHQFFGNLLAPKWWSYLWLNEGFARLYQYYLGAIS-HPELQLRERFVTGPFQTALRAD 403

  Fly   402 ALESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKN-AEQ 465
            ...:..|::...:....||..||.|:|.|.:.|||||:..|||.:|:.||:.|||:...:. .|:
Mosquito   404 NSLTVRPMTYYTETRPSISRLFDSIAYDKSACVLRMMNYALGERTFQKGLRYYLQQNKERGVVEE 468

  Fly   466 DNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQVAR 530
            .||::||.|||.:...||.|..|..|..||:.|.|.|::.|.||  .......||||:.||....
Mosquito   469 SNLFDSLEQAAKEDAVLPISLSIHEIFGSWSHQPGVPLVKVRRD--GNEYLFTQERYIANTPPEE 531

  Fly   531 AYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQLSTLYKV 595
            .:... ||:|:|::|.:...|.. .|..||.  .|...:..||:.:  .|:.|.||...:..|:|
Mosquito   532 PFENS-WWIPISFSTPSNNAFEK-LPAFWMP--PNVSEVAYTIETV--QDEVVSFNPHSTGYYRV 590

  Fly   596 NYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQREREYLPWK 660
            .|:....:.|||.: |.|........||:||||.|.:|.:...:|::.::|:.|||||.:|:||.
Mosquito   591 EYEESMLRELIERI-NKDHTGFEPATRARLIDDTLNIAQSRGGNYDVVLQLLNYLQRETDYVPWA 654

  Fly   661 SAFENLKRVGRIVRQTPDF-EFFKRYMKKLILPIYE-----HLNGINDTFSAIPQQDQVLLKTMV 719
            .|:|||:.:..::|..... :..:|:::|:..|:.|     |..|.:.:...        |:|:.
Mosquito   655 VAYENLRHMQSMLRTNEAVSQLLERFIEKIASPLLERYGVDHRTGESASVGE--------LRTIA 711

  Fly   720 VNWACQYQVGDCVPQA------LAYYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSDWEFL 778
            ::.||... ..|...|      ||..:::..|.|             .:.|..::..:....:.|
Mosquito   712 IDLACSGS-QSCKDDAQSAVRSLASKKHYTMEDN-------------ALLCHGLQQSNAEQRKSL 762

  Fly   779 WTRY------KKSNVAAEKRTILTALGC----SREVWLLQRYLELTFDPKEAIRKQDSMWAFQAV 833
            ..::      |..:..:.|:.:|.:|.|    ..:|....:|| |.....:..:....:.....|
Mosquito   763 QAQFSQVLSDKNLDNPSAKQFLLQSLSCLGGDMTKVQSFAKYL-LALSESDRTKALHRLLVELNV 826

  Fly   834 AFNEVGFLLAKKYFMDNVDFIYKFYHP-LTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQSLK 897
            ...|:...|..:......:.:|..:.| |..:::|.::..::..:..|..:.:..:|.:.
Mosquito   827 PLAEIVQSLQSELSQRRSNSVYYKHGPKLIFEIARYVTDPADVQLLSSVASSYDSWVASE----- 886

  Fly   898 GLEQAIQQTLEIMLTNVQWKERNYHQMSRSI 928
             :||.:.       .|:.|.|:|...:..::
Mosquito   887 -IEQQVN-------ANLNWVEQNVEPLKNAL 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	164/472 (35%)
		ERAP1_C	582..910	CDD:463368	72/350 (21%)
LOC1275101	XP_314331.5	None