Protein Alignment SP1029 and LOC1272139

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_311017.5
• Gene: LOC1272139 / 1272139
• VectorBaseID: AGAMI1_006784
• Length: 953
• Species: Anopheles gambiae
• Alignment Length: 947
• Identity: 248/947 - (26%)
• Similarity: 425/947 - (44%)
• Gaps: 122/947 - (12%)

  Fly    33 RLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHS-KNLTIDESQITLRQIG 96
            :|||.|.|..|.|.:..:|:..   .|||.|.|.:...:.|..:.||: .:||:||.::.:.:||
Mosquito    46 KLPTDLVPSGYSLHLHPVLDRS---IFSGRVNITLLCAKATNQINLHAHHDLTVDELELEVVRIG 107

  Fly    97 G-EGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQLEGYYRSSYK------ 154
            | ||..:..:......|.....::.....|.||..||:.:.|..::...:||.:...||
Mosquito   108 GAEGGTKVPIRRVDRVPKKPLLVIYFHDALTAGAAYEVRLRFVGNIWENVEGIFEGKYKQQQSTG 172

  Fly   155 --DPVANLTKWISV--------TQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEK 209
              :|....::.::.        |.|.|..||..|||||||.:|.||.|::...:.:..:.|...:
Mosquito   173 PSEPAGTESEGVTEPEEHSFIGTYFRPHHARRVFPCFDEPSYKVPFNVSIVRPRTHHVLFNTALE 237

  Fly   210 ---ETKPHETLADYIWCEFQESVPMSTYLVAYSVNDFSHKPSTLPN-------SALFRTWARPNA 264
               ||...:.:.|.    |:::.||||:...:.|:|......:|.:       ....|.|||.:.
Mosquito   238 RTVETGDGKHVIDV----FKQTAPMSTFTFGFLVSDLQQVTPSLSDEKEDERLKPTIRVWARRDF 298

  Fly   265 IDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFS-AGAMENWGLVTYREIALL---YSA 325
            ........|.....|:..::::|:..||.|:|.:|:|.|| ....:||||:.::|..|:   |:
Mosquito   299 QKNVADVQQRVKLALRKLQEYWGVPLPLEKLDVVALPGFSYVKPADNWGLIVFKESELMRGYYN- 362

  Fly   326 AHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQES 390
                          :|.||.:||.|:.:|..||:|..:|:..|.::                  |
Mosquito   363 --------------LAQELVYQWLGSWITPHWWSDAHVNKAIAGFL------------------S 395

  Fly   391 LSNLLTIFRRDALESSHPISRPIQMVSEISESF--DQISYQKGST-------VLRMMHLFLGEES 446
            ....:.|...|..|..:|::....:..|.|:.:  .:|:..|..|       ||||::..||||:
Mosquito   396 ADTAIKIDGGDEFEGKYPMTILYSIYYEFSKRYPHSRITAMKQETTCSKTELVLRMLNYTLGEET 460

  Fly   447 FRSGLQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYA 511
            ||.|||.::|...||....:::||:||:.||..:.|.:|..:..:::||..:...|::.|.|.||
Mosquito   461 FRRGLQRFIQHREYKTFYGEDVWEALTKQAHLDQRLCESVTVNDVVNSWITKDRIPMVRVVRSYA 525

  Fly   512 ARTAKLNQERYLLNT--QVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQ 574
            .|||.:.|..||...  .|....: ..||:||....|...:|.|.:...||:     :....|:.
Mosquito   526 NRTATVTQRLYLRERPHDVPEQDK-MLWWIPLVVVRQDRLNFGNVSTIRWMK-----QVREVTLD 584

  Fly   575 DLPGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFE-RIHVINRAQLIDDALYLAWTGEQ 638
            :|||||:::|.|.:....:.||||.:||.||...|...:.. .|.|..||:|:.||..||:.|:.
Mosquito   585 ELPGPDEFIIVNPEEIGPFPVNYDERNWNLLATFLQKEESRTMIPVYTRAKLLHDAWNLAYAGDL 649

  Fly   639 DYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNGINDT 703
            .:..|..:..:::.||.:|.|...|..:..:||.:..:...:.|:.|::.|:.|:||.|.|
Mosquito   650 SFGTAFNMTLFMKYERNHLVWNPVFTLIDHIGRHIDMSAVHKKFEMYVRTLLTPLYEELVG---- 710

  Fly   704 FSAIPQQD-----QVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVY 763
                .||:     :..|:::..|:.|:.....|:.:|...::.|....:||..||    |.:...
Mosquito   711 ----NQQESEEMWKANLRSLAKNFLCRAGYKPCIEEAQRAFKKWMDSPDPDAGNP----VANQFI 767

  Fly   764 CTSIKHGSDSDWEFLWTR---YKKSNVAAEKRTIL-TALGCSREVWLLQRYLE-LTFDPKEAIRK 823
            |...|.|:..:|||...|   :.:|.|.:|:..:| |..||..:.:.:.|.|. :..:.......
Mosquito   768 CPVFKWGTREEWEFGLQRVINFPESRVKSERTYLLKTLAGCPSQPFKIDRLLNIMVLEDNGNFTD 832

  Fly   824 QDSMWAFQAVAFNEVGFLLAKKYFMDNVDFI-YKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKD 887
            .|....|:.::....|:.....:..:|.|.| .:|     ||...|...:......|....|..|
Mosquito   833 NDISLIFKMLSGGSSGYSTLFNFLKNNWDAIKLRF-----KDRESLWDNMINSATGLFTTQEGYD 892

  Fly   888 FVNNSRQSLKG----LEQAIQQTLEIMLTNVQWKERN 920
            .|:......:|    .|..|:::|:.:....:|.:.|
Mosquito   893 MVSQLYVQHQGEFGTAEHIIEKSLKNIKEETKWSDEN 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	130/495 (26%)
		ERAP1_C	582..910	CDD:463368	84/343 (24%)
LOC1272139	XP_311017.5	None