Protein Alignment SP1029 and LOC1270378

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_309093.5
• Gene: LOC1270378 / 1270378
• VectorBaseID: AGAMI1_011814
• Length: 1133
• Species: Anopheles gambiae
• Alignment Length: 1066
• Identity: 244/1066 - (22%)
• Similarity: 413/1066 - (38%)
• Gaps: 251/1066 - (23%)

  Fly    34 LPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNLTIDESQITLRQIGGE 98
            ||.:::|.:|   |||:..|...|...|.|.|.:...:.|..|.||:::|.|.|..:    :|.:
Mosquito   126 LPNNVKPNRY---ILTIHPNLTTLDVKGQVSIELYVEKETNFVVLHAQDLNITEKAL----VGPK 183

  Fly    99 GKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAAD-LNRQLEGYYRSSYKDPVANLTK 162
            |.....:......|....|| .|.::|.....|.|.:.:.:. :..|.||.:         ::.|
Mosquito   184 GFALKILRMLEYTPRQQLYI-ETREKLRKKANYTLSIRWHSKMILDQFEGDF---------DMKK 238

  Fly   163 WISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLADYIWC---- 223
            .::.|..:|.|.|.||||||||..:|.|.::|...:.:..:||...::|   :.:..|:..
Mosquito   239 TLAATVLKPGSTRKAFPCFDEPHLRAAFKISLFRDRFHIGLSNSIVQDT---DDVGFYMGTGLLR 300

  Fly   224 -EFQESVPMSTYLVAYSVNDFSHK---------------------------PST----------- 249
             :|.|:.|:....|::.::||..:                           |||
Mosquito   301 DDFAETPPLPPDSVSWVISDFRRELLEPSAKYQKVNASGNGASAAGAGKVPPSTAGAGNGKSTPS 365

  Fly   250 ----------------LPNSALFR-----TWARPNAI--DQCDYAAQFGPKV------------- 278
                            |.:..||:     ....|..|  |....||:.||.|
Mosquito   366 KVTKTEKKPFRNLTAVLLSKNLFKLTNTAPTKEPTQIENDVTISAAESGPAVAKSNGTVLPEHDA 430

  Fly   279 -------------------------------------LQYYEQFFGIKFPLPKIDQIAVPDFSAG 306
                                                 |:|.:|:..:.:||.|:|.:|:|.....
Mosquito   431 LWNGDTALIRTAPAYSFYAPETHIAKGTFILHTSRDILEYLQQWLSVAYPLSKLDFVALPSLLDD 495

  Fly   307 AMENWGLVTYREIALLYSAAHSSLADKQRVASVV--AHELAHQWFGNLVTMKWWTDLWLNEGFAT 369
            ...:.|::..|...|....|.||   |:...|||  :..:..|:||.|::.|.|...||.||...
Mosquito   496 LSSSLGIIVCRTSFLNEPTAISS---KEYHMSVVKISEGIVKQYFGGLISPKVWKHKWLWEGLIR 557

  Fly   370 YVASLGVENINPEWRSMEQESLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQISY--QKGS 432
            |::...:..|.|.|...|...:..|......|||:....||      :..|:|.|...:  .|.:
Mosquito   558 YLSRFLLATIQPLWPMKELFLIDTLTKALDIDALQGWESIS------AGASDSGDNDPFYVDKSA 616

  Fly   433 TVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAH--KYRSLPKSYDIKSIMDSW 495
            .:|.|:...:||.:||..|..:|:.:.::.||..:||....:..:  ||        ::.:|:.|
Mosquito   617 ALLSMLQSAIGERNFRQCLGKFLKTYQFQTAEPSDLWAICAKQVNNSKY--------VREMMNQW 673

  Fly   496 TLQTGYPVINVTRDYAARTAK---LNQERYLL---------------------------NTQVAR 530
            |....:|::|||.:..:.|.:   .....||.                           .|..:.
Mosquito   674 TNTAAFPLLNVTMNGTSLTVRQTGFRPAEYLAIYDEPMEEIEREGEQGRSTTTTPAPVDATGKSG 738

  Fly   531 AYRGGCWWV-PLSYTTQAVQDFNNTAPKA----------WMECGKNGESLPKTIQDLPGPDQWVI 584
            :...|..|| |:.|.|. |.:.|.||.:|          |:...       :.|..|....||:.
Mosquito   739 SGEAGTRWVFPIHYITD-VLNTNETAAEAEHKEQQSLIIWLNSS-------EVIITLNHTAQWIK 795

  Fly   585 FNTQLSTLYKVNYDAQNWKLLIE--TLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLI 647
            .|...:..|:|.||..||..|:|  .:.|..|.   ..:|..|:.|...|..........||.||
Mosquito   796 LNHGQTGYYRVLYDEANWAKLVEQMQINNAVFS---TQDRVGLVSDIFTLCHANLIPCHAAMELI 857

  Fly   648 EYLQREREYLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNGINDTFSAIPQQDQ 712
            .|..:|:|:.|......:|::..:|::.:..:.....|:::.:....:.| |.:||    .:.:.
Mosquito   858 SYFPKEKEWGPIVLGTSHLEKWRKILKYSECYLVLAEYVRQNLAKSIQVL-GWDDT----GEDET 917

  Fly   713 VLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSDWEF 777
            .||:.:::..|..::..:.:..|.....|:...:     .|:|.|:||..|..|:..|....|:|
Mosquito   918 KLLRPVLMLSAALWEESETIKFAKGLVTNFTTHS-----IPIPPNLRSVAYIGSVLSGEFQYWQF 977

  Fly   778 LWTRY-----KKSNVAAEKRTILTALGCSREVWLLQRYLE--LTFDPKEAIRKQDSMWAFQAVAF 835
            .|.||     :||:|..|:..:|.|||.:::.||..|.|.  :|....|.::      ..:|:|.
Mosquito   978 CWDRYMTVRREKSSVLEERMELLRALGVTKDAWLQNRLLSHVITLPVFEIVQ------VLEAIAG 1036

  Fly   836 NEVG------FLLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQ 894
            ...|      ||.||.:     ||..|.... |...:|::|.:::...|..|::|.|..|.....
Mosquito  1037 TPTGGAMACRFLQAKWF-----DFQSKLGRG-TVQFARVISAITQYGSTKFDYDELKSLVERFGD 1095

  Fly   895 SLKGLEQAIQQTLEIMLTNVQWKERN 920
            . .|| :.:..||..:..||:|..|:
Mosquito  1096 G-PGL-KLLNMTLSTVAANVEWVSRS 1119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	128/577 (22%)
		ERAP1_C	582..910	CDD:463368	85/342 (25%)
LOC1270378	XP_309093.5	None