Protein Alignment SP1029 and LOC11175889

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_003436573.2
• Gene: LOC11175889 / 11175889
• VectorBaseID: AGAMI1_012506
• Length: 935
• Species: Anopheles gambiae
• Alignment Length: 928
• Identity: 286/928 - (30%)
• Similarity: 443/928 - (47%)
• Gaps: 112/928 - (12%)

  Fly    32 YRLPTSLRPQKYHLRILTLLE---NPEDLRFSGSVKILIEA-LENTKNVTLHSKNLTIDESQITL 92
            |||...:.|..|.:.|...||   |.....|.||.||.:.. .:|...:.||...:.|....:|
Mosquito    45 YRLNDDVWPTHYDIEIKPYLEQEGNKAQFTFDGSAKITVSTQKQNVMQIKLHMARMDITAWSVT- 108

  Fly    93 RQIGGEGKKENCVSST---AVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQLEGYYRSSYK 154
                  .|.:|.:..|   ..:.......|.....|.|...|.|...:..:::..:.|:|||.|.
Mosquito   109 ------RKSDNTIIPTLPQTYDQETQILTLPLSSALQANVEYVLSFTYVGNMDDDMHGFYRSYYW 167

  Fly   155 DPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHE---T 216
            :.  .:..|:..|||:...||.||||||||.|||.|.:.:.:..:|...||.....|...|   |
Mosquito   168 ED--GVKVWMGSTQFQQTHARRAFPCFDEPRFKATFQLKINHKTQYNVYSNTAIVGTAVAEVGRT 230

  Fly   217 LADYIWCEFQESVPMSTYLVA-----YSVNDFSHKPSTLPNSALFRTWARPNAIDQCDYAAQFGP 276
            |.     .|..:..||:||:|     |.:||...          ....|||.|.:|..|:...|.
Mosquito   231 LT-----TFGVTPSMSSYLIAFIVAPYQINDRDG----------MGILARPQAQNQTQYSLDVGI 280

  Fly   277 KVLQYYEQFFGIKFP------LPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQR 335
            |:|:..|::  |.:|      :.::...|||||||||||||||:||||..:||.:..|:...:.|
Mosquito   281 KLLKALEEW--IDYPYASVAGMTRMYMAAVPDFSAGAMENWGLLTYRETNILYRSDDSTSMQQHR 343

  Fly   336 VASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRR 400
            :|:|::||:||||||:|||.:||...|||||||.|....|...:..||....|..:..|..:.:.
Mosquito   344 IAAVISHEIAHQWFGDLVTCEWWDVTWLNEGFARYYQYYGTALVETEWNLDHQFVVEQLQGVMQM 408

  Fly   401 DALESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQ 465
            |:|.|:||::.|:...::.|..||.|||.||:.:||||..:|..|:|::.|:||::..::|....
Mosquito   409 DSLRSTHPMTHPVYTQAQASGIFDNISYNKGAVMLRMMEHYLTTETFKTALRAYIKDRAFKTTRP 473

  Fly   466 DNLWESLTQAAHKYRSLPKSYD--IKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLL---- 524
            ::|:.:|.:           ||  .:|.|:.||:|:|||::.||......|  :.|:|:|:
Mosquito   474 EDLFSALNR-----------YDPNARSYMEPWTIQSGYPLVTVTSHDTGFT--ITQKRFLVNEPD 525

  Fly   525 -NTQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQWVIFNTQ 588
             |.|:|       |.:|:::.|:| .:|:.|.|..:  .|...|...:...|:    ::.|.|.|
Mosquito   526 HNEQIA-------WPLPITFATKA-SEFSITRPAFY--TGMTFEIPMQGASDV----EYFILNNQ 576

  Fly   589 LSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQRE 653
            ....|:|||||..|..:.:.|.:..|..|||:||||::||...||......|..|:.::|||:.|
Mosquito   577 QVGYYRVNYDAILWGKISKALHSEGFGGIHVLNRAQIVDDLFNLARGDVVPYGTALEILEYLKEE 641

  Fly   654 REYLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNGINDTFSAIPQQDQVLLKTM 718
            .||.||.:|...|..:.|.: ...|.:.|..::..:....|:.:.     |.|....::.:...|
Mosquito   642 TEYAPWLAAVNGLTTLSRRI-HADDEKLFAAHILDIFSKAYDIVK-----FQAPTATERRIFTYM 700

  Fly   719 ---VVNWACQYQVGDCVPQALA----YYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSDWE 776
               |:.|||.|...:|...|:|    |::|...:.:||        :|..|||..|:.||..::|
Mosquito   701 RQNVLQWACNYGHEECSKAAVAEFHRYHQNPSVKVHPD--------LRQVVYCEGIRKGSTEEFE 757

  Fly   777 FLWTRYKKSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEVGFL 841
            |||.:|..:|||.|:..||..|||.....|:...|.....|.  :|.||...||..|..|.....
Mosquito   758 FLWNQYLTTNVATEQILILQGLGCVSSSELITDMLNGIASPH--VRSQDKNNAFTYVINNPYTLP 820

  Fly   842 LAKKYFMDN-VDFI--YKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQSL-KGLEQA 902
            ...:|...| .::.  :..|..:....:.:|:.|...    |:.:....|:.:::..| :....:
Mosquito   821 HVSRYLQQNHANWAASHGSYTNVASAFNNVLARLKSD----SERDAISAFIESNKNILGQAAYDS 881

  Fly   903 IQQTLEIMLTNVQWKERN 920
            |:..||...||.|:..||
Mosquito   882 IKSGLEDYETNKQFTLRN 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	157/477 (33%)
		ERAP1_C	582..910	CDD:463368	96/338 (28%)
LOC11175889	XP_003436573.2	None