Protein Alignment SP1029 and LOC11175624

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_003436699.2
• Gene: LOC11175624 / 11175624
• VectorBaseID: AGAMI1_004280
• Length: 939
• Species: Anopheles gambiae
• Alignment Length: 953
• Identity: 278/953 - (29%)
• Similarity: 463/953 - (48%)
• Gaps: 139/953 - (14%)

  Fly    32 YRLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSKNLTIDESQITLRQIG 96
            ||||:.:.|..|.|.:.|.: :..:..:||||.|.::..:..|.:.:|.:.|.|..:::
Mosquito    50 YRLPSYIVPTHYKLYLETQV-HTGNRSYSGSVDIHLDIRQQAKTIYVHQRGLRITSNEL------ 107

  Fly    97 GEGKKENCVSSTAVNPSHDFYILNT---------------CQELLAGNTYELYMPFAADLNRQLE 146
                       .|.||:.:...|.|               .:..||..:|.|::.|..:|....:
Mosquito   108 -----------YASNPNTNLTFLETLRYTEDAEREFAVFAIRRALAPASYVLHLDFEGELRVDDD 161

  Fly   147 GYYRSSYKDPVANLT-KWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKE 210
            |:|.|||.|  ||.| |:::.|||:..|||.||||.|||..||...:.:.:|..|.|:||||
Mosquito   162 GFYLSSYLD--ANGTRKYVASTQFQAISARAAFPCLDEPALKATVELGIKHHPSYKAVSNMP--- 221

  Fly   211 TKPHETLADYIWCE-----------FQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARPNA 264
                      |:.|           |:.:..||.||:|:.|:||.:   |...:|..|.:|||||
Mosquito   222 ----------IFAEAGDLDGNVVTYFETTPRMSIYLLAFLVSDFLY---TENEAAAQRVYARPNA 273

  Fly   265 IDQCDYAAQFGPKVLQYYEQFFGIKFP--LPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAH 327
            |:|..||.:.|.:::...::..|:.:.  :||:||:|:..|||||||||||..|||..||:....
Mosquito   274 INQTLYALEAGVRIMDALDEHIGLPYRSYMPKVDQVALTQFSAGAMENWGLCKYREEVLLFEPGV 338

  Fly   328 SSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLS 392
            ::...:..:.:::|||..||||||::|.:||:.|||||||||....||.:...||   .:...|.
Mosquito   339 TTYRAQTTITTIIAHEYVHQWFGNVITNEWWSYLWLNEGFATLYEFLGADMAYPE---RQYRDLF 400

  Fly   393 NLLTIFR---RDALESSHPI--SRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQ 452
            |:..:.|   .||.||:.|:  ||.... :.|...||.::|.||.:||:|..|.|.:.::|..|:
Mosquito   401 NVQVVQRVLITDAAESTRPMTFSRGATF-NAILSLFDNVAYSKGGSVLQMFRLLLPDAAWRQMLR 464

  Fly   453 AYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKL 517
            .|:|...:.....||...:||:|.....|||:..|::..:.||..|.||||:.|.|.|..... |
Mosquito   465 TYVQGNEFGTVNTDNFVAALTEAFDGVVSLPEGTDVERFVHSWVNQAGYPVLEVRRSYRGEII-L 528

  Fly   518 NQERYLLNTQVARAYRGGCWWVPLSYTTQA-VQDFNNTAPKAWMECGKNGESLPKTIQDLPGPDQ 581
            :|:|:..|..|...:.  .|.:|.:...|. .||    |...|.........:|.:..:    |:
Mosquito   529 SQDRFYSNKIVNNDFT--VWVIPYTMMEQGDAQD----ALLEWQWMTSKAVRVPSSTPN----DE 583

  Fly   582 WVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRL 646
            |::.|...:..|:||||..||.:||:||.. |...|.:.:|||||||:.:||.:...|.|||:.|
Mosquito   584 WILVNVNQTGFYRVNYDPSNWYMLIQTLLE-DTAAIPMHSRAQLIDDSFHLARSNRLDLEIALEL 647

  Fly   647 IEYLQREREYLPWKSAFENLKRV-----GRIVRQTPDFEFFKRYMKKLILPIYEHLNGINDTFSA 706
            :.|::.||||.||::|    .||     || :|..||:..::.::..||..::..|:     .:.
Mosquito   648 LGYVRHEREYPPWEAA----NRVLGYFHGR-MRGQPDYILYELFVDTLIGDVFVTLD-----ITT 702

  Fly   707 IPQQDQVL---LKTMVVNWACQYQVGDCVP---QALAYYRNWRAEANPDEKNPVPINVRSTVYCT 765
            :...:::|   |:.::.:|||:.::..|:.   .||        |....:..||..:|.:.|||.
Mosquito   703 VAPDERLLEKYLRQVISSWACRMEIESCLTATRDAL--------EREVFDAEPVHPDVSAVVYCY 759

  Fly   766 SIKHGSDSDWEFLWTRYKKSNVAAEKRTILTALGCSREVWLLQRY--------LELTFDPKEAIR 822
            .::......:::|:.:...|:...|::.::.||||:.:...|..|        |::.|:.:|.:.
Mosquito   760 GLRTAPTVAFQYLFGKLLGSDNRGERQLLINALGCANDTEQLSSYLLAAIGGELQVNFNAEERLS 824

  Fly   823 KQDSMWAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHP-----LTKDMSRLLSPLSEQVITLSDF 882
                  ..|:|..:..|.....::..:|..::.....|     |.:.::...:.|.|:.:.::..
Mosquito   825 ------ILQSVLSSRQGVDALIEFLTENYTYVVSLLGPNALANLVQSIATSTNTLDEEQMLIALL 883

  Fly   883 NEFKDF----VNNSRQSLKGLEQAIQQTLEIMLTNVQWKERNY 921
            .:....    |:.|.::...:..|...|.|.:|.....:..|:
Mosquito   884 EQLNSVLPASVSASARTTASINLAWPSTREGLLLRYFLERYNF 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	162/488 (33%)
		ERAP1_C	582..910	CDD:463368	87/355 (25%)
LOC11175624	XP_003436699.2	None