Protein Alignment SP1029 and rnpepl1

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: NP_001335117.1
• Gene: rnpepl1 / 100535895
• ZFINID: ZDB-GENE-030131-5522
• Length: 692
• Species: Danio rerio
• Alignment Length: 689
• Identity: 154/689 - (22%)
• Similarity: 247/689 - (35%)
• Gaps: 200/689 - (29%)

  Fly    63 VKILIEALENTKNVTLHSKNLTIDESQITLRQIGGEGKKENCVSST-AVNPSHDFYILNTCQELL 126
            |:.||  |:...::.:||.:..:.         |..|..:..:|.| .|.|..|:
Zfish    79 VQSLI--LDTHPSLLIHSVDCKVP---------GASGAPDVFLSLTYRVEPFTDY---------- 122

  Fly   127 AGNTYELYMPFAA-DLNRQLEGYYRSSYKDPVA----------NLTKWISVTQFEPASARLAFPC 180
             |::..:.:|.|. ..:|......|.:..|..|          ..|:.:..||......|..|||
Zfish   123 -GSSLNITLPAAVIRPHRAFRVTVRYTTTDGPAIWWLDAELTCGQTRPLVFTQGHSVCNRSFFPC 186

  Fly   181 FDEPDFKAPFVVTLGYHKKYTAISNMPEKETKPHETLADYIWCEFQESVPMSTYLVAYSVNDFSH 245
            ||.|..|:.:..|:...:..|.:.:.........:.:     .:|....|:..||||....|..|
Zfish   187 FDTPAVKSTYSATVRVPEGVTVLMSASRSAYSKQDRV-----FQFSMEYPVPAYLVALVAGDLQH 246

  Fly   246 KPSTLPNSALFRTWARP-----------NAIDQCDYAAQ--FGPKVLQYYEQFFGIKFPLPKIDQ 297
             ....|.|   |.||.|           .::::....|:  |||.|...|:..|     ||
Zfish   247 -ADIGPRS---RVWAEPCILTCAVSKLGGSVERWLNVAEGLFGPYVWGRYDLVF-----LP---- 298

  Fly   298 IAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQRVASV-VAHELAHQWFGNLVTMKWWTDL 361
               |.|...|||| ..:|:         ..||:.:.|....: |.||:||.||||.||...|.::
Zfish   299 ---PSFPIVAMEN-PCLTF---------IISSILESQEFLLIDVIHEIAHGWFGNAVTNATWEEM 350

  Fly   362 WLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQ- 425
            ||:||.|||..    ..|..|   ...|:.:.|.|:||.|||.....:......||::...|:.
Zfish   351 WLSEGLATYAQ----RRITTE---AYGEAFTCLETVFRLDALHRQMRLLGDNNPVSKLQAKFEPG 408

  Fly   426 ---------ISYQKGSTVLRMMHLFLGE-ESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAHKYR 480
                     .:|:||...:..:....|: :.|.|.|:||::||.:.:....:|.:.....
Zfish   409 VNPSSLMNLFTYEKGFCFVSYLSQLCGDIKRFDSFLRAYIEKFRFSSVIAQDLLDFFLGF----- 468

  Fly   481 SLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQVARAYRGGCWWVPLSYTT 545
                                :|  .:.....|:...|..||:|          .|| ..||
Zfish   469 --------------------FP--ELKEGCVAQREGLEFERWL----------NGC-GPPL---- 496

  Fly   546 QAVQDFNNTAPKAWMECGKN---GESLPKTIQ---DLPG---PDQWVIFNTQLSTLYKVNYDAQN 601
                            |..:   |.:|...:|   ||.|   ||..||     ||     :|..:
Zfish   497 ----------------CEPDLSAGRTLTGPVQHLCDLWGNDAPDTQVI-----ST-----FDLSS 535

  Fly   602 WKLLIETLTNGDFERIHVINRAQLIDDAL------YLAWTGEQDYEIAMRLIEYLQREREYLPWK 660
            |. ..:|:...|    .:::|:.|..:.:      |.|...:.:.|:.:|.::.:.|       .
Zfish   536 WS-TFQTVLFLD----RLLDRSPLSQEVMSLLSSCYAALLDDMNAEVQIRWLQIVVR-------N 588

  Fly   661 SAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNG 699
            |.:.:|.||...:.        |...:...:|:||.|.|
Zfish   589 SFYPDLPRVRSFLH--------KHTSRMYTVPLYEDLCG 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	110/470 (23%)
		ERAP1_C	582..910	CDD:463368	25/124 (20%)
rnpepl1	NP_001335117.1	M1_LTA4H	36..490	CDD:341062	116/507 (23%)
		Leuk-A4-hydro_C	536..649	CDD:462686	20/104 (19%)