Protein Alignment SP1029 and erap1

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_002933475.2
• Gene: erap1 / 100496768
• XenbaseID: XB-GENE-983344
• Length: 932
• Species: Xenopus tropicalis
• Alignment Length: 934
• Identity: 299/934 - (32%)
• Similarity: 482/934 - (51%)
• Gaps: 80/934 - (8%)

  Fly    18 ADSSADSIET-TYNYYRLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALENTKNVTLHSK 81
            |..:.|:.|. .:...||||...|..|.|.|   ..|...|.|||..|:.:...:.|..:.||||
 Frog    36 ASKALDNAEMFPWKNLRLPTFAAPLHYDLLI---HPNLTTLTFSGLTKVTVTVTQKTSFLVLHSK 97

  Fly    82 NLTIDESQITLRQIGGEGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFAADLNRQLE 146
            :|.|.::.|. |::|.:...::.:  ...:|.::...|.....|:.|..|.:|:.:.|:|::...
 Frog    98 HLEITKTTIK-RKLGKDPVLQDLL--LREHPVNEQIALLAADPLIPGENYTIYIEYNANLSKNFR 159

  Fly   147 GYYRSSYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKET 211
            |:|:|:||.....: :.::.|||||.:||.||||||||.|||.|.:.:....|:.|:||||..:|
 Frog   160 GFYKSTYKTKDGEV-RVLASTQFEPTAARTAFPCFDEPAFKASFSIQIRREPKHHAVSNMPVVKT 223

  Fly   212 K--PHETLADYIWCEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARPNAIDQCDYAAQF 274
            .  ....|.|:    |..||.|||||||:.|:||........:......:|.|..|||.:||.:.
 Frog   224 VNIGGGLLEDH----FAASVKMSTYLVAFIVSDFKSISQVTNHGVRISVYATPEKIDQAEYALKA 284

  Fly   275 GPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYSAAHSSLADKQRVASV 339
            ..|:|.:||.:|.|.:||||.|..|:|||.:||||||||.||||.|||:....|:.:.|..|..:
 Frog   285 AVKLLDFYEDYFNISYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLHDPKTSTASHKLWVTMI 349

  Fly   340 VAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRRDALE 404
            :|||||||||||||||:||.|||||||||.::..:.|....||.: :|...|.........|:|.
 Frog   350 IAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEYVSVRVTYPELQ-VEDYFLDKCFRAMDVDSLN 413

  Fly   405 SSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLW 469
            |||.:|.|::...||.|.||::||.||:.:|.|:..::|.|||.:|:..||:::||:||..::||
 Frog   414 SSHAVSTPVENPEEIQEMFDEVSYDKGACILNMLMDYMGAESFEAGIVDYLRRYSYRNARNEDLW 478

  Fly   470 ESLT-----------------QAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKL 517
            .|:|                 |.:|  .|..:..|:||:|::||||.|:|::.||  ...:...|
 Frog   479 NSMTDVCPSDETNSGYCTKTRQTSH--WSEGEIIDVKSMMNTWTLQKGFPLVTVT--VKGKYVYL 539

  Fly   518 NQERYLLNTQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKT-IQDLPGPDQ 581
            :||.||..:....| .|..|.:||:|.|..    :||..:..:        :.|| :..|....:
 Frog   540 HQEHYLKGSTDTEA-SGLLWHIPLTYITSK----SNTVQRFLL--------MSKTDVLVLAEEVE 591

  Fly   582 WVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRL 646
            |:.||..::..|.|:|:.:.|..||:.|.. :...|...:||.||:.|..|...|....:.|:.|
 Frog   592 WIKFNVGMNGYYIVHYEGEGWDALIKLLQE-NHTAISSNDRANLINSAFQLVSIGRLPIDKALSL 655

  Fly   647 IEYLQREREYLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHL---NGINDTFSAIP 708
            ..||:.|.:.:|.....:.|..:.:::.:. |.:..:..|||.||.:...|   ....|..|.
 Frog   656 SLYLKNEDKIMPVFQGMDELIPIYKLMEKR-DMQEVESQMKKYILNLLRKLIDAQSWTDEGSV-- 717

  Fly   709 QQDQVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKN---PVPINVRSTVYCTSIKHG 770
              .:.:|::.::.:||..|...||.:|..|::.|:      |.|   .:|.:|.|.||....:
 Frog   718 --SERMLRSSLLLFACVRQYQPCVQRAEQYFKRWQ------ESNGTISLPRDVASAVYAVGAQ-- 772

  Fly   771 SDSDWEFLWTRYKKSNVAAEKRTILTALGCS----REVWLLQRYLELTFDPKEAIRKQDSMWAFQ 831
            :...|:||:.:||.:...:||..|..||..:    :..||::..::     .:.:|.||......
 Frog   773 TPEGWDFLFEKYKTTLSGSEKNQIELALAITSLKHKLQWLMEEGMK-----GDHVRTQDLPHIVL 832

  Fly   832 AVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQSL 896
            .|:.|.||:.|:.::..:|...:.:.:...::.:..::..:::|..|.....|...|.::.::..
 Frog   833 YVSRNPVGYPLSWEFLKNNWGNLVQKFELGSRTVGDMVVGITKQYSTKEWLEEVTGFFDSLKEMG 897

  Fly   897 KGLEQAIQQTLEIMLTNVQWKERN 920
            ..| :.:||..|.:..|::|.::|
 Frog   898 SQL-RCVQQARETIEENIRWMDKN 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	185/473 (39%)
		ERAP1_C	582..910	CDD:463368	79/337 (23%)
erap1	XP_002933475.2	M1_APN-Q_like	60..521	CDD:341064	185/474 (39%)
		ERAP1_C	592..911	CDD:463368	79/338 (23%)