Protein Alignment SP1029 and anpep

DIOPT Version :10

• Sequence 1: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Sequence 2: XP_031755081.1
• Gene: anpep / 100492262
• XenbaseID: XB-GENE-981369
• Length: 977
• Species: Xenopus tropicalis
• Alignment Length: 939
• Identity: 322/939 - (34%)
• Similarity: 497/939 - (52%)
• Gaps: 74/939 - (7%)

  Fly    16 ATADSSADSIETT--YNYYRLPTSLRPQKYHLRILT-LLENPEDLR-FSGSVKILIEALENTKNV 76
            |||.::|.:.::.  :|.||||.:|.|..|.:.:.. |::|.:.|. |.|.........:.|..:
 Frog    65 ATATATATTAQSNDPWNKYRLPKTLSPVHYDVELQPFLVKNADGLYVFRGKSTAFFICNDATDLI 129

  Fly    77 TLHSKNLT---IDESQITLRQIGGEGKKENCVSSTAVNPSHDFYILNTCQELLAGNTYELYMPFA 138
            .:||..|.   .:.....|:    :|..:..:.||.......|.::.....|:.|..|.||..|.
 Frog   130 IIHSNKLNHTKFNSFDAKLQ----DGATDVALKSTFFQKDKQFLVVQAAANLVPGKQYGLYTEFV 190

  Fly   139 ADLNRQLEGYYRSSYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAI 203
            .:|...|.|:|||.|.:.  .:||.|:.||.:...||.||||||||..||.|.:||.|.:.|.|:
 Frog   191 GELADDLAGFYRSEYLED--GVTKIIATTQMQAPDARKAFPCFDEPAMKATFNITLKYRQPYKAM 253

  Fly   204 SNMPEKETKPHETLAD----YIWCEFQESVPMSTYLVAYSVNDFSHKPSTLPNSAL---FRTWAR 261
            |||.|.:   ..|:.:    :...:|.::..||:||||:.|::|.....  |.:|.   .:.|.|
 Frog   254 SNMREID---RSTVTEDGQQWTVSKFDKTPKMSSYLVAFIVSEFEAVGD--PGNATVTGVQIWGR 313

  Fly   262 PNAI---DQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLY 323
            ..||   :|.:||......:|.::.:::...:||||.||:|:||||||||||||||||||.|||:
 Frog   314 KKAIQDENQGEYALSVTKPILDFFAEYYRTPYPLPKSDQVALPDFSAGAMENWGLVTYRETALLF 378

  Fly   324 SAAHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQ 388
            ....||:.:|:||.:|:||||||||||||||::||.|||||||||:||..||.:...|.|...:.
 Frog   379 DDQVSSIGNKERVVTVIAHELAHQWFGNLVTIRWWNDLWLNEGFASYVEYLGADKAEPNWNIKDL 443

  Fly   389 ESLSNLLTIFRRDALESSHPISR---PIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSG 450
            ..|:::..:...|||.||||::.   .:...||||..||.|:|.||::|:||:..||.|..|..|
 Frog   444 IVLNDVHRVMAVDALASSHPLTSREDEVNSPSEISALFDSIAYSKGASVIRMLSEFLTEPLFVDG 508

  Fly   451 LQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTA 515
            |.:||:.|.|.|....:||..|..|.:...::.....||.|||:|.||.|:||:.:  |.|  |.
 Frog   509 LASYLKGFEYSNTVYSDLWTHLQWAVNNQTAVKLPLPIKDIMDTWVLQMGFPVVKI--DTA--TG 569

  Fly   516 KLNQERYLL--NTQVARA----YRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQ 574
            .:.|:.:||  ::.|.|.    |:   |.||:||...:.:|      ..|::    .||  :|::
 Frog   570 VVTQKHFLLDPDSVVTRPSPFDYK---WKVPISYKISSKED------NIWLQ----NES--ETVE 619

  Fly   575 D--LPGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGE 637
            |  :.|.| |::.|..::..|:||||..||..|:..|.. ..:.|.||||||:||||..||...:
 Frog   620 DFKITGND-WLLVNLNVTGYYRVNYDDNNWSRLLNQLQT-SHQAIPVINRAQIIDDAFNLARAKQ 682

  Fly   638 QDYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHL----- 697
            .....|:...:|:..:|||:||::|...|....::..:|..|...|:|||..:.|::|:.
 Frog   683 ITTIQALDTTKYISADREYMPWQAALSGLSYFTQMFDRTEVFGPMKKYMKMQVNPLFEYFKQETG 747

  Fly   698 NGINDTFSAIPQQDQVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTV 762
            |..|...|...|..::    ..::.||.|.:.||:..|...:..|.  |.|.:.|..| |:|:.|
 Frog   748 NWTNRPVSLTDQYCEI----NTLSTACSYDIEDCLKFASELFSQWM--ATPQQNNIHP-NLRTNV 805

  Fly   763 YCTSIKHGSDSDWEFLWTRYKKSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSM 827
            |||::..|.:.:|.|:|.|::.:::|.|:..:..||.||:|.|:|.|:||.:.|| ..||:||::
 Frog   806 YCTAVAQGGEQEWNFVWDRFQLTDIAQEQDKLRAALACSKEPWILNRFLEYSLDP-TMIRRQDAV 869

  Fly   828 WAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDF-VNN 891
            ....:|..|.:|..||..:.......:|..:...:.....|:..::.:..|..:..:...| .:|
 Frog   870 STISSVVNNPIGQSLAWDFVRAKWKTLYSMFGESSFSFGNLIERVTRRFSTEFELQQLLQFKADN 934

  Fly   892 SRQSLKGLEQAIQQTLEIMLTNVQWKERN 920
            .........||::|.:|....|:.|..:|
 Frog   935 QNPGFGTASQALEQAIEKTKANINWVNQN 963

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	182/472 (39%)
		ERAP1_C	582..910	CDD:463368	99/333 (30%)
anpep	XP_031755081.1	M1_APN-Q_like	92..555	CDD:341064	182/473 (38%)
		ERAP1_C	628..955	CDD:463368	99/335 (30%)