DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aplip1 and ldlrap1

DIOPT Version :9

Sequence 1:	NP_728573.1	Gene:	Aplip1 / 53472	FlyBaseID:	FBgn0040281	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_001017114.1	Gene:	ldlrap1 / 549868	XenbaseID:	XB-GENE-954261	Length:	309	Species:	Xenopus tropicalis

Alignment Length:	153	Identity:	39/153 - (25%)
Similarity:	66/153 - (43%)	Gaps:	17/153 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   330 LDYNEFDPTVQLVKKERYLLGYLGSVETLAHKGTGVVCQAVRKIVG-EYGNSPTGQTCILEVSDQ 393
            |..|..|....|::...:.|.|||.......||..:...||::||. ...:....|..||:||.:
Frog    30 LPENWTDTRETLLEGMSFHLKYLGMTLVEQPKGEELSATAVKRIVATAKASGKKLQKVILKVSPR 94

  Fly   394 GLRMVDRSGPNQNKKDKKPCIDYFYSLKNVSFCAFHPRDHRFIGFITKHPTVQRFACHVF----- 453
            |:.:.|.:. ||..::        .|:..:|:|.......:...:|.:....:...||.|
Frog    95 GIILYDLAS-NQLIEN--------VSIYRISYCTADKMHDKVFAYIAQSQQNETLECHAFLCTKR 150

  Fly   454 KGSES-TRPVAEAVGRAFQRFYQ 475
            |.::: |..||:|...||: |:|
Frog   151 KMAQAVTLTVAQAFKVAFE-FWQ 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aplip1	NP_728573.1	SH3_JIP1_like	275..329	CDD:212735
Aplip1	NP_728573.1	PTB_JIP	343..490	CDD:269923	35/140 (25%)
ldlrap1	NP_001017114.1	PTB_LDLRAP-mammal-like	43..165	CDD:269981	31/130 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910