Protein Alignment Aplip1 and Ldlrap1

DIOPT Version :10

• Sequence 1: NP_728573.1
• Gene: Aplip1 / 53472
• FlyBaseID: FBgn0040281
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001102741.1
• Gene: Ldlrap1 / 500564
• RGDID: 1563417
• Length: 307
• Species: Rattus norvegicus
• Alignment Length: 154
• Identity: 38/154 - (24%)
• Similarity: 65/154 - (42%)
• Gaps: 19/154 - (12%)

  Fly   330 LDYNEFDPTVQLVKKERYLLGYLGSVETLAHKGTGVVCQAVRKIVG-EYGNSPTGQTCILEVSDQ 393
            |..|..|....|::...:.|.|||.......||..:...||::||. ...:....|...|:||.:
  Rat    30 LPENWTDTRETLLEGMVFSLKYLGMTLVERPKGEELSAAAVKRIVATAKASGKKLQKVTLKVSPR 94

  Fly   394 GLRMVDRSGPNQNKKDKKPCIDYFYSLKNVSFCAFHPRDHRFIGFITKHPTVQRFACHVFKGSES 458
            |:.:.| |..:|..::        .|:..:|:|.......:...:|.:....:...||.|..::
  Rat    95 GIILTD-SLTSQLIEN--------VSIYRISYCTADKMHDKVFAYIAQSQQNESLECHAFLCTK- 149

  Fly   459 TRPVAEA----VGRAFQ---RFYQ 475
             |.||:|    |.:||:   .|:|
  Rat   150 -RKVAQAVTLTVAQAFKVAFEFWQ 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aplip1	NP_728573.1	SH3_JIP1_like	275..329	CDD:212735
		PTB_JIP	343..490	CDD:269923	34/141 (24%)
Ldlrap1	NP_001102741.1	PTB_LDLRAP-mammal-like	43..165	CDD:269981	31/132 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..205
		Clathrin box. /evidence=ECO:0000250|UniProtKB:Q5SW96	211..215
		AP-2 complex binding. /evidence=ECO:0000250|UniProtKB:Q5SW96	248..275
		[DE]-X(1,2)-F-X-X-[FL]-X-X-X-R motif. /evidence=ECO:0000250|UniProtKB:Q5SW96	256..265