DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aplip1 and fam43b

DIOPT Version :9

Sequence 1:	NP_728573.1	Gene:	Aplip1 / 53472	FlyBaseID:	FBgn0040281	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_001004547.1	Gene:	fam43b / 447808	ZFINID:	ZDB-GENE-040912-11	Length:	303	Species:	Danio rerio

Alignment Length:	150	Identity:	43/150 - (28%)
Similarity:	67/150 - (44%)	Gaps:	22/150 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   339 VQLVKKE-RYLLGYLGSVETLAHKGTGVVCQAVRKI--VGEYGNSPTGQTCILEVSDQGLRM-VD 399
            |:|.|:| .|.:.||||..|:..||.....:||.||  ...||.......  :.|...|:|| ||
Zfish    63 VELNKEEPTYNVRYLGSAVTIVAKGEDCTQEAVAKIWTRSNYGEQSAKMK--ITVGPHGIRMGVD 125

  Fly   400 RSGPNQNKKDKKPCIDYFYSLKNVSFCAFHPRDHRFIGFITKHPTVQR---FACH--VFKGSEST 459
            :||      .|||  .:.:||..:::|...|...:.:.:|.:|....:   ..||  :...:|..
Zfish   126 KSG------KKKP--SHLFSLNRITYCTADPFRPKILAWIYRHQVKNKAVVLRCHAVLLAKAEKA 182

  Fly   460 RPVAEAVGRAFQRFYQKFIE 479
            |.:|.::   :|.....|.|
Zfish   183 RALALSL---YQNTTSAFTE 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aplip1	NP_728573.1	SH3_JIP1_like	275..329	CDD:212735
Aplip1	NP_728573.1	PTB_JIP	343..490	CDD:269923	40/145 (28%)
fam43b	NP_001004547.1	PH-like	71..254	CDD:302622	38/141 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573993
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840