Protein Alignment Aplip1 and C1orf226

DIOPT Version :9

• Sequence 1: NP_728573.1
• Gene: Aplip1 / 53472
• FlyBaseID: FBgn0040281
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001128712.1
• Gene: C1orf226 / 400793
• HGNCID: 34351
• Length: 315
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 61/265 - (23%)
• Similarity: 92/265 - (34%)
• Gaps: 65/265 - (24%)

  Fly    67 VDH---EPKMRQVEDDELGDGLKVTLSSDGSLDTNDSFNSHRHHPLNHQDAIGGFLGMDTSGLGG 128
            |.|   ||..|.| |..:.:.|...|:.  .|..:.|| .|...|:..        |....|.|.
Human    28 VSHLLSEPLSRTV-DHGMFENLNTALTP--KLQASRSF-PHLSKPVAP--------GSAPLGSGE 80

  Fly   129 NSAP-VTIGASTDLLAPNTAATRRRRKLPEIPKNKKSSILHLLGGSNFGSLADEFRNGGGGGIPP 192
            ...| :.:|:|..|   .........|:.:..:.|:.|.|..:|.:.....|......|....|.
Human    81 PGGPGLWVGSSQHL---KNLGKAMGAKVNDFLRRKEPSSLGSVGVTEINKTAGAQLASGTDAAPE 142

  Fly   193 A----VRSGQQRSFLSLKCGYLMDEDSSPDSERMQS-----------------LGDVDSGHSTAH 236
            |    .||..|.:|..|        |..|...|.::                 |..::.|  |..
Human   143 AWLEDERSVLQETFPRL--------DPPPPITRKRTPRALKTTQDMLISSQPVLSSLEYG--TEP 197

  Fly   237 SPNDFKSMSPQITSPVSQSPFPPPFGGVPFGQLEMLEATHRGLHKFVPRHHDEIELEIGDAIYVQ 301
            ||.     ..|.::|.:| |..|.....|...:|..|   ||  |.:|  :.|:.|.:.|.|:
Human   198 SPG-----QAQDSAPTAQ-PDVPADASQPEATMEREE---RG--KVLP--NGEVSLSVPDLIH-- 247

  Fly   302 KEAED 306
            |:::|
Human   248 KDSQD 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aplip1	NP_728573.1	SH3_JIP1_like	275..329	CDD:212735	10/32 (31%)
		PTB_JIP	343..490	CDD:269923
C1orf226	NP_001128712.1	DUF4628	44..315	CDD:292069	54/248 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141121
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930