Protein Alignment Aplip1 and POSH

DIOPT Version :10

• Sequence 1: NP_728573.1
• Gene: Aplip1 / 53472
• FlyBaseID: FBgn0040281
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_523776.1
• Gene: POSH / 36990
• FlyBaseID: FBgn0040294
• Length: 838
• Species: Drosophila melanogaster
• Alignment Length: 324
• Identity: 68/324 - (20%)
• Similarity: 124/324 - (38%)
• Gaps: 67/324 - (20%)

  Fly    28 SKKNNPHAFYSLIPNDDLEDSHSSKSDGDGSDQEDGIGLVDHEPKMRQVEDDELGDGL----KVT 88
            |:|:.|.      |......:.||.|.|       .:||:.....|: ......|..|    |..
  Fly   552 SRKSEPK------PETATASTTSSSSSG-------AVGLMRRLTHMK-TRSKSPGASLQQVPKEA 602

  Fly    89 LSSDGSLDTNDSFNSHRHH--------PLNHQDAIGGFLGMDTSGLGGNSAPVTI-GASTDLLAP 144
            :|::....||.|...|..|        .|.|...:.......|:.......|..: .|||:.::.
  Fly   603 ISTNVEFTTNPSAKLHPVHVRSGSCPSQLQHSQPLNETPAAKTAAQQQQFLPKQLPSASTNSVSY 667

  Fly   145 NTAATRRRRKLPEIPKNKKSSILHLLGGSNFGSLADEFRNGGG-----GGIPPAVRSGQQRSFL- 203
            .:...:..::.|.:...::|     |..:.|.|:   :.|...     ..:.|||.:|.|:..:
  Fly   668 GSQRVKGSKERPHLICARQS-----LDAATFRSM---YNNAASPPPPTTSVAPAVYAGGQQQVIP 724

  Fly   204 ------SLKCGYLMDEDSSPDSERMQSLGDVDSGHSTAHSPNDFKSMSPQITSPVSQSPFPPPFG 262
                  .|....::    :|...:..||   |:.|..:.|.|.....:.: .|..::||:.
  Fly   725 GGGAQSQLHANMII----APSHRKSHSL---DASHVLSPSSNMITEAAIK-ASATTKSPYC---- 777

  Fly   263 GVPFGQLEMLEATHRGLHKFVPRHHDEIELEIGDAIYVQKEAEDLWCEGVNLRTGRQGIFPSAY 326
                    ..|:..|.:..:.|....|:||.:||.||||::.::.|.:|.:.||.:.|:||:::
  Fly   778 --------TRESRFRCIVPYPPNSDIELELHLGDIIYVQRKQKNGWYKGTHARTHKTGLFPASF 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aplip1	NP_728573.1	SH3_JIP1_like	275..329	CDD:212735	18/52 (35%)
		PTB_JIP	343..490	CDD:269923
POSH	NP_523776.1	RAD18	6..>113	CDD:227719
		RING-HC_SH3RF3	8..53	CDD:438408
		SH3	139..191	CDD:473055
		SH3_SH3RF_2	199..251	CDD:212721
		SH3_SH3RF_3	424..477	CDD:212717
		SH3_SH3RF_C	782..836	CDD:212719	18/52 (35%)