Protein Alignment Aplip1 and jip-1

DIOPT Version :9

• Sequence 1: NP_728573.1
• Gene: Aplip1 / 53472
• FlyBaseID: FBgn0040281
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001364697.1
• Gene: jip-1 / 173513
• WormBaseID: WBGene00002176
• Length: 1001
• Species: Caenorhabditis elegans
• Alignment Length: 428
• Identity: 134/428 - (31%)
• Similarity: 204/428 - (47%)
• Gaps: 97/428 - (22%)

  Fly   113 DAIGGFLGMD---------TSGLGGNSAPVTIGASTDL-----------LAPNTAATRRRRKLPE 157
            |.|....||:         |:|:|...|...|.....|           :.|:...:...|:||.
 Worm   621 DTIRQSSGMETRTINSTTGTNGIGSAGAAGKIDPCAHLETPISPHIFQSVLPSPTPSSSGRRLPA 685

  Fly   158 IPKNKKSSILHLLGGSNFGSLADEFRNGGGGGIPP----------------AVRSGQQRSFLSLK 206
            :|.|..:.:..:...|                |||                ...|..:||.|.::
 Worm   686 LPINSAALLRRIPMAS----------------IPPNPPQKHQDHQLCFMDGMADSMMERSSLGME 734

  Fly   207 CGYLMDEDSSPDSERMQSLGDVDSGHSTAHSPNDFKSMSPQITSPVSQSPFPPPFGGVPFGQLEM 271
            ..|..::..:.:..|.|.       ..:..||:|...:|...||. ||:|
 Worm   735 DSYYEEDGINGNRRRRQQ-------RKSFFSPDDSSGVSSCTTSD-SQNP--------------- 776

  Fly   272 LEATHRGLHKFVPRHHDEIELEIGDAIYVQKEAEDLWCEGVNLRTGRQGIFPSAYAVDLDYNE-- 334
               |||....|.|||.||:.||||||::|.:.|:|.|..|.|||||:.||||::...::|..|
 Worm   777 ---THRVQSAFHPRHPDELLLEIGDAVHVDRTADDHWSYGTNLRTGQSGIFPASIVCEIDLVEEI 838

  Fly   335 ---FDPT--VQLVKKER--YLLGYLGSVETLAHKGTGVVCQAVRKIVGEYGNSP---TGQTCILE 389
               ..||  .:::..:|  :.|..|.|:|...|||..|:.||:.|::..|.||.   ..||.::|
 Worm   839 CLGALPTNATKILSGDRDTFYLTMLASIEVAHHKGNDVLTQAMNKVLSMYKNSEEIIVPQTVLME 903

  Fly   390 VSDQGLRMVDRSGPNQNKKD--KKPCIDYFYSLKNVSFCAFHPRDHRFIGFITKHPTVQRFACHV 452
            :|.:|:.::|:     .:|:  :.|..|:||||:|:|||..||:..::.|||||||.:.||||||
 Worm   904 ISFRGIHVIDK-----RRKNFFQCPMFDFFYSLQNISFCGAHPKQLKYFGFITKHPLLPRFACHV 963

  Fly   453 FKGSESTRPVAEAVGRAFQRFYQKFIETAYPIEDIYIE 490
            |....:|:|:.||:||||:|.|.:::..|:|.||||:|
 Worm   964 FMSKNTTQPIVEAIGRAFKRSYDEYMAFAHPTEDIYLE 1001

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aplip1	NP_728573.1	SH3_JIP1_like	275..329	CDD:212735	29/53 (55%)
		PTB_JIP	343..490	CDD:269923	64/153 (42%)
jip-1	NP_001364697.1	SH3_JIP1_like	777..831	CDD:212735	29/53 (55%)
		PTB_JIP	855..1001	CDD:269923	64/150 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159765
Domainoid	1	1.000	108	1.000	Domainoid score	I4068
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D360087at33208
OrthoFinder	1	1.000	-	-		FOG0003016
OrthoInspector	1	1.000	-	-		oto17493
orthoMCL	1	0.900	-	-		OOG6_108705
Panther	1	1.100	-	-	LDO	PTHR11232
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3474
SonicParanoid	1	1.000	-	-		X2453
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.880