DRSC/TRiP Functional Genomics Resources

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Protein Alignment Aplip1 and FAM43B

DIOPT Version :9

Sequence 1:NP_728573.1 Gene:Aplip1 / 53472 FlyBaseID:FBgn0040281 Length:490 Species:Drosophila melanogaster
Sequence 2:NP_997217.1 Gene:FAM43B / 163933 HGNCID:31791 Length:329 Species:Homo sapiens


Alignment Length:171 Identity:46/171 - (26%)
Similarity:68/171 - (39%) Gaps:28/171 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   315 RTGRQGIFPSAYAVDLDYNEFDPTVQLVKKERYLLGYLGSVETLAHKGTGVVCQAVRKIVGEYGN 379
            |.||  :|.|. ...::.|:.|||        |.:.|||:..||..||.|....||.||....| 
Human    51 RLGR--VFRSR-RQKVELNKEDPT--------YTVWYLGNAVTLHAKGDGCTDDAVGKIWARCG- 103

  Fly   380 SPTGQTCI-LEVSDQGLRM--VDRSGPNQNKKDKKPCIDYFYSLKNVSFCAFHPRDHRFIGFITK 441
             |.|.|.: |.:...|:||  .:||... ....::|.  :.|.|..:::|....|..|...::.:
Human   104 -PGGGTKMKLTLGPHGIRMQPCERSAAG-GSGGRRPA--HAYLLPRITYCTADGRHPRVFAWVYR 164

  Fly   442 HPTVQR---FACH------VFKGSESTRPVAEAVGRAFQRF 473
            |....:   ..||      ..|.....|.:.:....||..|
Human   165 HQARHKAVVLRCHAVLLARAHKARALARLLRQTALAAFSDF 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Aplip1NP_728573.1 SH3_JIP1_like 275..329 CDD:212735 5/13 (38%)
PTB_JIP 343..490 CDD:269923 37/143 (26%)
FAM43BNP_997217.1 PH-like 71..263 CDD:418428 38/148 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 245..329
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165141117
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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