Protein Alignment Aplip1 and mapk8ip1a

DIOPT Version :10

• Sequence 1: NP_728573.1
• Gene: Aplip1 / 53472
• FlyBaseID: FBgn0040281
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001338595.2
• Gene: mapk8ip1a / 100537717
• ZFINID: ZDB-GENE-101025-1
• Length: 759
• Species: Danio rerio
• Alignment Length: 524
• Identity: 153/524 - (29%)
• Similarity: 240/524 - (45%)
• Gaps: 95/524 - (18%)

  Fly    17 HTIAGFGSGAGSKKNNPHAFYSLIPNDDLEDSHSSKSDGDGSDQEDGIGLVDHEPKMRQVEDDEL 81
            ||:.|:.........|......|:  |..:|.|.|:.:.........:......|.:.|..|..
Zfish   281 HTVNGYREQVQYPAENEGMCDQLV--DRNKDYHISEGNATEEIHLTPVNGEQERPFLSQSSDSN- 342

  Fly    82 GDGLKVTLSSDGSLDTNDSFNSHRHHPLNHQDAIGGFLGMDTSGLGGNSAPVTIGASTDLLAPNT 146
                ::::|||..|.           ||::..:.|              .|....:..|.:.|.|
Zfish   343 ----RMSISSDTELP-----------PLHYYPSAG--------------CPNPSISEEDEVYPPT 378

  Fly   147 ------------------AATRRRRKLPEIPKNKKSSILHLLGGSNFGSLA-DEFRNGGGGGIPP 192
                              |.||:    |::.|::..::..:...::...|. |..:      ...
Zfish   379 PPCRTVSLSEQPGDSSQWAETRK----PKMAKDETGNVKAVAVSTDASGLTYDSVK------YTL 433

  Fly   193 AVRSGQQRSFLSLK-C--GYLMDED-----SSPDSERMQSLGDVDSGHSTAHS-PNDFKSMS--- 245
            .|....:...:|:| |  ||..|.|     |:.|.:......|.:...|.|.| ..|...:|
Zfish   434 VVDEHAKLELVSIKDCYKGYESDSDNTVYESAIDEDDEDQEADEEDEESGARSMRRDTSCLSADS 498

  Fly   246 -PQITSPVSQS-PFPPPFG-------GVPFGQL------EMLEATHRGLHKFVPRHHDEIELEIG 295
             ...||.|.:| .|...||       |..||..      |..|.:||.:.:|||||.||:|||..
Zfish   499 TTDTTSDVPRSRKFMNIFGNGRSRFSGAEFGFFSCVINGEEREQSHRAVFRFVPRHDDELELEAD 563

  Fly   296 DAIYVQKEAEDLWCEGVNLRTGRQGIFPSAYAVDLDYNEFDPTVQLVKKERYLLGYLGSVETLAH 360
            |.:.|:.:|||||||..|:|||.:||||:.|||.:..:|....|:....:::.:.:||||:...|
Zfish   564 DPLLVELQAEDLWCEAYNMRTGTRGIFPAFYAVKVAKDELVKEVKGDWMDKFWVKFLGSVQVPYH 628

  Fly   361 KGTGVVCQAVRKIVGEYGN----SPTGQTCILEVSDQGLRMVDRSGPNQNKKDKKPCIDYFYSLK 421
            ||..|:|.|:.||......    ||. ..||:|::.:||::|.:.....:.:.:| |. :|:.||
Zfish   629 KGNDVLCAAMHKIASNRRTTMQFSPP-SPCIVEINTRGLKIVVQDDCRTSGRGEK-CF-HFFQLK 690

  Fly   422 NVSFCAFHPRDHRFIGFITKHPTVQRFACHVFKGSESTRPVAEAVGRAFQRFYQKFIETAYPIED 486
            |:|||..||:::::.|.|||||..||||||||...::|..:||:||:|||:||::.:|.:.|.||
Zfish   691 NISFCGCHPKNNKYFGLITKHPANQRFACHVFFSDDTTTKLAESVGKAFQQFYKEHMEYSCPTED 755

  Fly   487 IYIE 490
            |::|
Zfish   756 IFLE 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aplip1	NP_728573.1	SH3_JIP1_like	275..329	CDD:212735	31/53 (58%)
		PTB_JIP	343..490	CDD:269923	60/150 (40%)
mapk8ip1a	NP_001338595.2	None