Protein Alignment SP555 and SPSB4

DIOPT Version :9

• Sequence 1: NP_001260073.1
• Gene: SP555 / 53471
• FlyBaseID: FBgn0260470
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_543138.1
• Gene: SPSB4 / 92369
• HGNCID: 30630
• Length: 273
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 80/286 - (27%)
• Similarity: 125/286 - (43%)
• Gaps: 65/286 - (22%)

  Fly    18 AIAPRRRRPTGRRGGVTGGLSSGSLDASSSTSPPPRFCPLPNGVEDNWTWSKRHRSKEVVLRGPN 82
            |:.|.:|...|...|....|.. .||..::..          .|:....|:...||..|.::..:
Human    18 ALRPAKRELRGAEPGRPARLDQ-LLDMPAAGL----------AVQLRHAWNPEDRSLNVFVKDDD 71

  Fly    83 SRTVHFHPNWSKGTAGVQGKRSLNNGRHYWELHVSQRVFGTSIMFGIGTKSARLHANAFRNMLGE 147
            ..|.|.|| .::.|.|::||.....|.|.|:::...|..||..:.|:.|..|.||:..:..::|.
Human    72 RLTFHRHP-VAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPLHSVGYTALVGS 135

  Fly   148 NEHGWGLS-HKGVLWHEGVALLYTKRFRENQ-----------------PTQIGVLFDGIEGTLTF 194
            :...||.. .:..|:|:|          :||                 |..:.|:.|..||||:|
Human   136 DAESWGWDLGRSRLYHDG----------KNQPGVAYPAFLGPDEAFALPDSLLVVLDMDEGTLSF 190

  Fly   195 YKDGKCLGVAFRGLDQIDEPLYPIVCSTAAKTEMTLKCTRREFVN--------LQDRCRAVIMRR 251
            ..||:.||||||||.  .:.|||:|.:.....|:|::     ::|        |.|.||    |.
Human   191 IVDGQYLGVAFRGLK--GKKLYPVVSAVWGHCEVTMR-----YINGLDPEPLPLMDLCR----RS 244

  Fly   252 VRSAAQLEKLK----LPLP--IADYL 271
            :|||...::|:    ||||  :.:||
Human   245 IRSALGRQRLQDISSLPLPQSLKNYL 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP555	NP_001260073.1	SPRY_SOCS3	64..249	CDD:293936	60/210 (29%)
		SOCS	240..273	CDD:295349	15/38 (39%)
SPSB4	NP_543138.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		5/15 (33%)
		SPRY_SOCS1-2-4	54..227	CDD:293963	55/190 (29%)
		SOCS	232..273	CDD:383010	15/43 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810