Protein Alignment SP555 and SPSB3

DIOPT Version :9

• Sequence 1: NP_001260073.1
• Gene: SP555 / 53471
• FlyBaseID: FBgn0260470
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: XP_005255730.1
• Gene: SPSB3 / 90864
• HGNCID: 30629
• Length: 410
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 101/292 - (34%)
• Similarity: 150/292 - (51%)
• Gaps: 38/292 - (13%)

  Fly     2 SDVEVDPQQAH-PHPIAAIAPRRRRPTGRRGGVTG-------GLSSGSLDASSSTSPPPRFCPLP 58
            ||.:.||:.:. |..|.:..|           |||       |.|..|..:|..::...|.|..
Human    99 SDSDSDPEYSTLPPSIPSAVP-----------VTGESFCDCAGQSEASFCSSLHSAHRGRDCRC- 151

  Fly    59 NGVED---NWTWSKRHRSKEVVLRGPNSRTVHFHPNWSKGTAGVQGKRSLNNGRHYWELHVSQRV 120
             |.||   :|.|...::|...:|...| |.|.||..:|.|||.::|.:.|..|:|:||:.::..|
Human   152 -GEEDEYFDWVWDDLNKSSATLLSCDN-RKVSFHMEYSCGTAAIRGTKELGEGQHFWEIKMTSPV 214

  Fly   121 FGTSIMFGIGTKSARL--HANAFRNMLGENEHGWGLSHKGVLWHEGVALLYTKRFRENQPTQIGV 183
            :||.:|.||||....|  :.:.|.::||.:|..||||:.|:|.|:|....::.||  .|.:.|||
Human   215 YGTDMMVGIGTSDVDLDKYRHTFCSLLGRDEDSWGLSYTGLLHHKGDKTSFSSRF--GQGSIIGV 277

  Fly   184 LFDGIEGTLTFYKDGKCLGVAFRGLDQIDEPLYPIVCSTAAKTEMTLKCTRREFVNLQDRCRAVI 248
            ..|...|||||:|:.||:|||...|.  ::..||:||||||::.|.:..:.....:||..| ...
Human   278 HLDTWHGTLTFFKNRKCIGVAATKLQ--NKRFYPMVCSTAARSSMKVTRSCASATSLQYLC-CHR 339

  Fly   249 MRRVR--SAAQLEKLKLPLPIADYLSEVIDEK 278
            :|::|  |...||.|.||    ..|.:|:..|
Human   340 LRQLRPDSGDTLEGLPLP----PGLKQVLHNK 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP555	NP_001260073.1	SPRY_SOCS3	64..249	CDD:293936	71/186 (38%)
		SOCS	240..273	CDD:295349	12/34 (35%)
SPSB3	XP_005255730.1	SPRY_SOCS3	159..341	CDD:293936	71/187 (38%)
		SOCS_SOCS_like	328..367	CDD:239687	13/43 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770