Protein Alignment SP555 and SPSB1

DIOPT Version :9

• Sequence 1: NP_001260073.1
• Gene: SP555 / 53471
• FlyBaseID: FBgn0260470
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_079382.2
• Gene: SPSB1 / 80176
• HGNCID: 30628
• Length: 273
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 77/283 - (27%)
• Similarity: 119/283 - (42%)
• Gaps: 73/283 - (25%)

  Fly    33 VTGGLSSGSLDASSSTSPPPR-------FC------------PLPNGVEDNWTWSKRHRSKEVVL 78
            ||||:.  ::|....|..|.:       :|            |:...|:...:|:...||..|.:
Human     5 VTGGIK--TVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNNDRSLNVFV 67

  Fly    79 RGPNSRTVHFHPNWSKGTAGVQGKRSLNNGRHYWELHVSQRVFGTSIMFGIGTKSARLHANAFRN 143
            :..:....|.|| .::.|..::||.....|.|.|::..:.|..||..:.|:.|..|.||:..:..
Human    68 KEDDKLIFHRHP-VAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTT 131

  Fly   144 MLGENEHGWGLS-HKGVLWHEGVALLYTKRFRENQPTQ-----------------IGVLFDGIEG 190
            ::|.|...||.. .:..|:|:|          :|||::                 ..|..|..:|
Human   132 LVGNNHESWGWDLGRNRLYHDG----------KNQPSKTYPAFLEPDETFIVPDSFLVALDMDDG 186

  Fly   191 TLTFYKDGKCLGVAFRGLDQIDEPLYPIVCSTAAKTEMTLKCTRREFVN--------LQDRCRAV 247
            ||:|..||:.:|||||||.  .:.|||:|.:.....|:     |..::|        |.|.||
Human   187 TLSFIVDGQYMGVAFRGLK--GKKLYPVVSAVWGHCEI-----RMRYLNGLDPEPLPLMDLCR-- 242

  Fly   248 IMRRVRSAAQLEKL----KLPLP 266
              |.||.|...|:|    .||||
Human   243 --RSVRLALGRERLGEIHTLPLP 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP555	NP_001260073.1	SPRY_SOCS3	64..249	CDD:293936	57/210 (27%)
		SOCS	240..273	CDD:295349	14/31 (45%)
SPSB1	NP_079382.2	SPRY_SOCS1-2-4	54..227	CDD:293963	52/190 (27%)
		SOCS_SSB1	232..273	CDD:239713	14/36 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810