Protein Alignment SP555 and Spsb1

DIOPT Version :10

• Sequence 1: NP_723047.1
• Gene: SP555 / 53471
• FlyBaseID: FBgn0260470
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_083311.1
• Gene: Spsb1 / 74646
• MGIID: 1921896
• Length: 273
• Species: Mus musculus
• Alignment Length: 283
• Identity: 77/283 - (27%)
• Similarity: 119/283 - (42%)
• Gaps: 73/283 - (25%)

  Fly    33 VTGGLSSGSLDASSSTSPPPR-------FC------------PLPNGVEDNWTWSKRHRSKEVVL 78
            ||||:.  ::|....|..|.:       :|            |:...|:...:|:...||..|.:
Mouse     5 VTGGIK--TVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNNDRSLNVFV 67

  Fly    79 RGPNSRTVHFHPNWSKGTAGVQGKRSLNNGRHYWELHVSQRVFGTSIMFGIGTKSARLHANAFRN 143
            :..:....|.|| .::.|..::||.....|.|.|::..:.|..||..:.|:.|..|.||:..:..
Mouse    68 KEDDKLIFHRHP-VAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYTT 131

  Fly   144 MLGENEHGWGLS-HKGVLWHEGVALLYTKRFRENQPTQ-----------------IGVLFDGIEG 190
            ::|.|...||.. .:..|:|:|          :|||::                 ..|..|..:|
Mouse   132 LVGNNHESWGWDLGRNRLYHDG----------KNQPSKTYPAFLEPDETFIVPDSFLVALDMDDG 186

  Fly   191 TLTFYKDGKCLGVAFRGLDQIDEPLYPIVCSTAAKTEMTLKCTRREFVN--------LQDRCRAV 247
            ||:|..||:.:|||||||.  .:.|||:|.:.....|:     |..::|        |.|.||
Mouse   187 TLSFIVDGQYMGVAFRGLK--GKKLYPVVSAVWGHCEI-----RMRYLNGLDPEPLPLMDLCR-- 242

  Fly   248 IMRRVRSAAQLEKL----KLPLP 266
              |.||.|...|:|    .||||
Mouse   243 --RSVRLALGKERLGAIPALPLP 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP555	NP_723047.1	SPRY_SOCS3	64..249	CDD:293936	57/210 (27%)
		SOCS	240..273	CDD:470605	14/31 (45%)
Spsb1	NP_083311.1	SPRY_SOCS1-2-4	54..227	CDD:293963	52/190 (27%)
		SOCS	232..273	CDD:470605	14/36 (39%)