Protein Alignment SP555 and spsb4a

DIOPT Version :10

• Sequence 1: NP_723047.1
• Gene: SP555 / 53471
• FlyBaseID: FBgn0260470
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_001243571.1
• Gene: spsb4a / 557906
• ZFINID: ZDB-GENE-070911-3
• Length: 277
• Species: Danio rerio
• Alignment Length: 289
• Identity: 81/289 - (28%)
• Similarity: 120/289 - (41%)
• Gaps: 69/289 - (23%)

  Fly    33 VTGGLSSGSLDASSSTSP-------PPRFCPL---------PNGVED--NWTWSKRHRSKEVVLR 79
            ::|.:.|..:....|..|       |..|.|.         |...|.  ...|:...||..:.::
Zfish     5 ISGSIKSVDVRGEPSFRPLRRELRGPDFFKPARLDLLLDMPPASYEQQLRHAWNSDDRSLNIFIK 69

  Fly    80 GPNSRTVHFHPNWSKGTAGVQGKRSLNNGRHYWELHVSQRVFGTSIMFGIGTKSARLHANAFRNM 144
            ..:..|.|.|| .::.|.|::|:.....|.|.|.:|...|..||..:.|:.|..|.||:..:.::
Zfish    70 DDDKLTFHRHP-VAQSTDGIRGRVGYTRGLHVWRIHWPARQRGTHAVVGVATGDAPLHSVGYTSL 133

  Fly   145 LGENEHGWGLSHKGVLWHEGVALLYTK-------------RFRENQ-----PTQIGVLFDGIEGT 191
            :|.:...||       |..|...||..             .|.|.:     |..:.|:.|..|||
Zfish   134 VGSDSESWG-------WDLGRNKLYHNSKNRPASSAPTYPSFLEPEEAFVLPDTLMVVLDMDEGT 191

  Fly   192 LTFYKDGKCLGVAFRGLDQIDEPLYPIVCSTAAKTEMTLKCTRREFVN--------LQDRCRAVI 248
            |:|..||:.||||||||.  .:.|||||.:.....|:|::     ::|        |.|.||
Zfish   192 LSFMVDGQYLGVAFRGLK--GKKLYPIVSAVWGHCEITMR-----YINGLDPEPLPLMDLCR--- 246

  Fly   249 MRRVRSAAQLEKLK----LPLP--IADYL 271
             |..|.|...|:|:    ||||  :.:||
Zfish   247 -RAARLALGRERLQEIETLPLPQSLKNYL 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP555	NP_723047.1	SPRY_SOCS3	64..249	CDD:293936	61/210 (29%)
		SOCS	240..273	CDD:470605	15/38 (39%)
spsb4a	NP_001243571.1	SPRY_SOCS1-2-4	55..231	CDD:293963	56/190 (29%)
		SOCS_SSB1_4	236..277	CDD:239688	15/43 (35%)