DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SP555 and fbxo45

DIOPT Version :9

Sequence 1:	NP_001260073.1	Gene:	SP555 / 53471	FlyBaseID:	FBgn0260470	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_956889.1	Gene:	fbxo45 / 393567	ZFINID:	ZDB-GENE-040426-1450	Length:	291	Species:	Danio rerio

Alignment Length:	172	Identity:	54/172 - (31%)
Similarity:	82/172 - (47%)	Gaps:	28/172 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 SKEVVLRGPNSRTVHFHPNWSKGTAGVQGKRSLNNGRHYWELHVSQRVFGTSIMFGIGTKSARLH 137
            |:.|.:: .|..|:|.:| .::.|.|.:||...:.|||.||:. .:...||..:.||.||.|.:.
Zfish   125 SRNVYIK-KNGFTLHRNP-IAQSTDGARGKIGFSEGRHAWEIW-WEGPLGTVAVIGIATKRAPMQ 186

  Fly   138 ANAFRNMLGENEHGWG-------LSHKGVLWHEGVALLYTKRFRE--NQPT-QIG----VLFDGI 188
            ...:..:||.::..||       |.|.|.:         ...|.:  |.|. |||    |:.|..
Zfish   187 CQGYVALLGSDDQSWGWNLVDNNLLHNGEV---------NGNFPQCNNAPKYQIGERIRVILDMD 242

  Fly   189 EGTLTFYKDGKCLGVAFRGLDQIDEPLYPIVCSTAAKTEMTL 230
            :.||.|.:..:.||||||||.:  ..|:|.|.:....||:|:
Zfish   243 DKTLAFERGFEFLGVAFRGLPK--TCLFPAVSAVYGNTEVTM 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SP555	NP_001260073.1	SPRY_SOCS3	64..249	CDD:293936	54/172 (31%)
SP555	NP_001260073.1	SOCS	240..273	CDD:295349
fbxo45	NP_956889.1	F-box-like	44..90	CDD:289689
fbxo45	NP_956889.1	SPRY_Fbox	117..291	CDD:293964	54/172 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810