Protein Alignment SP555 and Spsb4

DIOPT Version :10

• Sequence 1: NP_723047.1
• Gene: SP555 / 53471
• FlyBaseID: FBgn0260470
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_660116.1
• Gene: Spsb4 / 211949
• MGIID: 2183445
• Length: 273
• Species: Mus musculus
• Alignment Length: 227
• Identity: 71/227 - (31%)
• Similarity: 112/227 - (49%)
• Gaps: 34/227 - (14%)

  Fly    67 WSKRHRSKEVVLRGPNSRTVHFHPNWSKGTAGVQGKRSLNNGRHYWELHVSQRVFGTSIMFGIGT 131
            |:...||..|.::..:..|.|.|| .::.|.|::||.....|.|.|::|...|..||..:.|:.|
Mouse    56 WNPEDRSLNVFVKDDDRLTFHRHP-VAQSTDGIRGKVGHARGLHAWQIHWPARQRGTHAVVGVAT 119

  Fly   132 KSARLHANAFRNMLGENEHGWGLS-HKGVLWHEG---VALLYTKRFRENQ----PTQIGVLFDGI 188
            ..|.||:..:..::|.:...||.. .:..|:|:|   ..:.|......::    |..:.|:.|..
Mouse   120 ARAPLHSVGYTALVGSDSESWGWDLGRSRLYHDGKNRPGVAYPAFLGPDEAFALPDSLLVVLDMD 184

  Fly   189 EGTLTFYKDGKCLGVAFRGLDQIDEPLYPIVCSTAAKTEMTLKCTRREFVN--------LQDRCR 245
            ||||:|..||:.||||||||.  .:.|||:|.:.....|:|::     ::|        |.|.||
Mouse   185 EGTLSFIVDGQYLGVAFRGLK--GKKLYPVVSAVWGHCEVTMR-----YINGLDPEPLPLMDLCR 242

  Fly   246 AVIMRRVRSAAQLEKLK----LPLP--IADYL 271
                |.:|||...::|:    ||||  :.:||
Mouse   243 ----RSIRSALGRQRLRDIGSLPLPQSLKNYL 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP555	NP_723047.1	SPRY_SOCS3	64..249	CDD:293936	60/197 (30%)
		SOCS	240..273	CDD:470605	15/38 (39%)
Spsb4	NP_660116.1	SPRY_SOCS1-2-4	54..227	CDD:293963	55/178 (31%)
		SOCS	232..273	CDD:470605	15/43 (35%)