Protein Alignment SP555 and Spsb2

DIOPT Version :10

• Sequence 1: NP_723047.1
• Gene: SP555 / 53471
• FlyBaseID: FBgn0260470
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_038567.1
• Gene: Spsb2 / 14794
• MGIID: 1315199
• Length: 264
• Species: Mus musculus
• Alignment Length: 280
• Identity: 75/280 - (26%)
• Similarity: 110/280 - (39%)
• Gaps: 69/280 - (24%)

  Fly    37 LSSGSLDASSSTSPPPRFCPLPNGVEDNWTWSKRHRSKEVVLRGPNSRTVHFHPNW--------- 92
            |:.||....:|.:....|.| |.|:|            |::...|.......|..|
Mouse     6 LARGSSSTPTSQALYSDFSP-PEGLE------------ELLSAPPPDLVAQRHHGWNPKDCSENI 57

  Fly    93 --------------SKGTAGVQGKRSLNNGRHYWELH--VSQRVFGTSIMFGIGTKSARLHANAF 141
                          ::.|.||:|||..:.|.|.||:.  :.||  ||..:.|:.|..|.|.|:.:
Mouse    58 DVKEGGLCFERRPVAQSTDGVRGKRGYSRGLHAWEISWPLEQR--GTHAVVGVATALAPLQADHY 120

  Fly   142 RNMLGENEHGWGLS-HKGVLWHEGVAL---LYTKRFRENQ---PTQIGVLFDGIEGTLTFYKDGK 199
            ..:||.|...||.. .:|.|:|:...|   .|....:..|   |.::.|:.|..||||.:...|.
Mouse   121 AALLGSNSESWGWDIGRGKLYHQSKGLEAPQYPAGPQGEQLVVPERLLVVLDMEEGTLGYSIGGT 185

  Fly   200 CLGVAFRGLDQIDEPLYPIVCSTAAKTEMTLKC--TRR-----EFVNLQDRCRAVIMRRVRSA-- 255
            .||.|||||.  ...|||.|.:...:.::.::.  .||     ..::|...|       ||.|
Mouse   186 YLGPAFRGLK--GRTLYPSVSAVWGQCQVRIRYMGERRVEEPQSLLHLSRLC-------VRHALG 241

  Fly   256 ----AQLEKLKLPLPIADYL 271
                .|:..|.||..:..||
Mouse   242 DTRLGQISTLPLPPAMKRYL 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SP555	NP_723047.1	SPRY_SOCS3	64..249	CDD:293936	57/223 (26%)
		SOCS	240..273	CDD:470605	11/38 (29%)
Spsb2	NP_038567.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		10/40 (25%)
		SPRY_SOCS1-2-4	46..217	CDD:293963	50/174 (29%)
		SOCS_SSB2	223..264	CDD:239689	11/46 (24%)