DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SP555 and si:dkey-23n7.10

DIOPT Version :9

Sequence 1:	NP_001260073.1	Gene:	SP555 / 53471	FlyBaseID:	FBgn0260470	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	XP_002662894.2	Gene:	si:dkey-23n7.10 / 100333689	ZFINID:	ZDB-GENE-141222-64	Length:	228	Species:	Danio rerio

Alignment Length:	222	Identity:	88/222 - (39%)
Similarity:	133/222 - (59%)	Gaps:	18/222 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 EDNWTWSKRHRSKEV---VLRGPNSRTVHFHPN---WSKGTAGVQGKRSLNNGRHYWELHVSQRV 120
            :::|.|....:|.:.   |.|    :.|:||.:   .|:|||||:|.:...:|.||||:...:..
Zfish    10 QESWEWDPDSKSPDAHVSVCR----QAVYFHISPLLDSQGTAGVRGTKGFTHGEHYWEIEFLEPP 70

  Fly   121 FGTSIMFGIGTKSARLHA--NAFRNMLGENEHGWGLSHKGVLWHEGVALLYTKRFRENQPTQIGV 183
            :|:|:|.|:||::|.||.  ..|.|::|.:...||||:||.:||:|.:..||:.|.|.. |.|||
Zfish    71 YGSSVMVGVGTQNALLHTGDQTFVNLIGMDSESWGLSYKGYIWHKGRSRKYTEAFYERN-TVIGV 134

  Fly   184 LFDGIEGTLTFYKDGKCLGVAFRGLDQIDEPLYPIVCSTAAKTEMTLKCTRREFVNLQDRCRAVI 248
            |.|...|||||.::|..|||||.||:|:.:.|||:|.|||.:||:.|....:...:||:.|..:|
Zfish   135 LLDLSAGTLTFSRNGVNLGVAFTGLEQVGKALYPLVSSTAPETELQLGLRSQRISSLQEHCIHII 199

  Fly   249 MRRVRSAAQLEKLK-LPLPIADYLSEV 274
               .:|.:|..:.| |||| |..|.::
Zfish   200 ---TQSLSQGRRAKGLPLP-ASLLCQI 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SP555	NP_001260073.1	SPRY_SOCS3	64..249	CDD:293936	78/192 (41%)
SP555	NP_001260073.1	SOCS	240..273	CDD:295349	13/33 (39%)
si:dkey-23n7.10	XP_002662894.2	SPRY_SOCS3	13..199	CDD:293936	78/190 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595041
Domainoid	1	1.000	114	1.000	Domainoid score	I6071
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H124681
Inparanoid	1	1.050	151	1.000	Inparanoid score	I4325
OMA	1	1.010	-	-		QHG47458
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0012077
OrthoInspector	1	1.000	-	-		oto38739
orthoMCL	1	0.900	-	-		OOG6_112817
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X9948
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.800