Protein Alignment PLIN1 and Plin1

DIOPT Version :10

• Sequence 1: NP_002657.3
• Gene: PLIN1 / 5346
• HGNCID: 9076
• Length: 522
• Species: Homo sapiens
• Sequence 2: NP_001295074.1
• Gene: Plin1 / 25629
• RGDID: 3351
• Length: 518
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 427/525 - (81%)
• Similarity: 459/525 - (87%)
• Gaps: 10/525 - (1%)

Human     1 MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSA 65
            |::|||.||||||||||||||||||||||||||||||||||.|||||||||||||||||||||.|
  Rat     1 MSMNKGPTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYNSTKEAHPLVASVCNAYEKGVQGA 65

Human    66 SSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNS 130
            |:||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||
  Rat    66 SNLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKGTISTRLRSARNS 130

Human   131 ISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPD 195
            |||||||||||||||.|||||||.|:|::|||:|||||.||||||||||||||||||||||||||
  Rat   131 ISVPIASTSDKVLGATLAGCELALGMAKETAEYAANTRVGRLASGGADLALGSIEKVVEYLLPPD 195

Human   196 KEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSL 260
            |.||||:.|.|:.||:||||||||.||..|.|||||:|:||.||||::||::|||||||.|||||
  Rat   196 KVESAPSSGRQKMQKAPKAKPSLLRRVSTLANTLSRHTMQTTARALKRGHSLAMWIPGVAPLSSL 260

Human   261 AQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDT---EEEEELETEENKFSEV 322
            ||||||.|||.||||:|||||||||:|||:::|:||||||||||:|   |||||.|.|||...||
  Rat   261 AQWGASAAMQVVSRRQSEVRVPWLHNLAASKDENHEDQTDTEGEETDEEEEEEESEAEENVLREV 325

Human   323 AALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDAL 387
            .|||.|.|.||||.||:|||||.||||||||||||||..||:||||||.||||||||||||||||
  Rat   326 TALPTPLGFLGGVVHTVQKTLQNTISAVTWAPAAVLGTVGRILHLTPAQAVSSTKGRAMSLSDAL 390

Human   388 KGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQP 452
            |||||||||||||||||||||||||||||:|||||||||     ||:.||:..|.||...|..||
  Rat   391 KGVTDNVVDTVVHYVPLPRLSLMEPESEFQDIDNPPAEV-----ERKGSGSRPASPESTARPGQP 450

Human   453 RRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQ 517
            |.||||.:...||..|.|:|:..|.|  ||||.|:|||||.||||||||||||||||||||.|||
  Rat   451 RGSLRSVRGLSAPSCPDLDDKTETSA--RPGFLAMPREKPARRVSDSFFRPSVMEPILGRTQYSQ 513

Human   518 LRKKS 522
            |||||
  Rat   514 LRKKS 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLIN1	NP_002657.3	Perilipin	13..414	CDD:460784	345/403 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..217		14/21 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..318		23/33 (70%)
		Required for interaction with CIDEC. /evidence=ECO:0000250	291..319		21/30 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..522		71/108 (66%)
Plin1	NP_001295074.1	Perilipin	13..417	CDD:460784	345/403 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..217		12/19 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..321		24/35 (69%)
		Required for interaction with CIDEC. /evidence=ECO:0000250	291..322		21/30 (70%)