DRSC/TRiP Functional Genomics Resources

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Protein Alignment PLIN1 and abu-6

DIOPT Version :10

Sequence 1:NP_002657.3 Gene:PLIN1 / 5346 HGNCID:9076 Length:522 Species:Homo sapiens
Sequence 2:NP_504383.1 Gene:abu-6 / 178903 WormBaseID:WBGene00000029 Length:388 Species:Caenorhabditis elegans


Alignment Length:239 Identity:37/239 - (15%)
Similarity:77/239 - (32%) Gaps:58/239 - (24%)


- Green bases have known domain annotations that are detailed below.


Human    22 QRVLQLPVVSGTC------ECFQKTYT--STKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVR 78
            |:..|:.|.|..|      .|.|:...  |..:..|.....|.|....:.:..:....:..|||:
 Worm    69 QQTQQVQVQSTQCAPACQQSCQQQCQASPSVSQCQPQCQQQCQAQCTPMYNPPTTTTTTQAPVVQ 133

Human    79 RLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVL 143
            ....|.....:  |:. ..::::.||.|..|:                                 
 Worm   134 YQQCQPVCQQQ--CQS-TCVQQQQPAAQCQPQ--------------------------------- 162

Human   144 GAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESAPAPGHQQA 208
                  |:....||.|:.  :..|:|.::.....::.....:      ..|..::...:...||.
 Worm   163 ------CQQQCNVACDSP--STTTQAPQVIQIQLEIQQAQAQ------CQPQCQQQCQSSCVQQQ 213

Human   209 QKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIP 252
            |:|.:.:|:..::...:....::.|.|...:.:.|.....|:.|
 Worm   214 QQSNQCEPACNTQCSDICQQTAQATQQVYNQNMNQNTNTQMYNP 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PLIN1NP_002657.3 Perilipin 13..414 CDD:460784 37/239 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 195..217 4/21 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 287..318
Required for interaction with CIDEC. /evidence=ECO:0000250 291..319
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 413..522
abu-6NP_504383.1 None
Blue background indicates that the domain is not in the aligned region.

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