DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HGTX and HB-1

DIOPT Version :9

Sequence 1:	NP_001368954.1	Gene:	HGTX / 53446	FlyBaseID:	FBgn0040318	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_186796.1	Gene:	HB-1 / 821138	AraportID:	AT3G01470	Length:	272	Species:	Arabidopsis thaliana

Alignment Length:	197	Identity:	49/197 - (24%)
Similarity:	74/197 - (37%)	Gaps:	55/197 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   434 NPIAWRERLSNTMSANLSQSHQHHP-------------SNDKDGKKKHTRPTFSGQQIFALEKTF 485
            ||:.......:.|  |:.::.:..|             .:|:..:||....|   :|:..|||:|
plant    25 NPVVQGGGARSMM--NMEETSKRRPFFSSPEDLYDDDFYDDQLPEKKRRLTT---EQVHLLEKSF 84

  Fly   486 EQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWR-KRHAAEMATAKRKQDDMGGDNDGDCSE 549
            |....|....:.:||..||:...||.|||||||.:|: |:...:....|...|.:..:.|   |.
plant    85 ETENKLEPERKTQLAKKLGLQPRQVAVWFQNRRARWKTKQLERDYDLLKSTYDQLLSNYD---SI 146

  Fly   550 TMDSD---------NESLD---------MGESPAQNK---------------RCRSNSSGSSQQQ 581
            .||:|         .|.|.         .|:.|..|:               |..|.|.||:...
plant   147 VMDNDKLRSEVTSLTEKLQGKQETANEPPGQVPEPNQLDPVYINAAAIKTEDRLSSGSVGSAVLD 211

  Fly   582 QD 583
            .|
plant   212 DD 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709
HGTX	NP_001368954.1	Homeobox	469..523	CDD:395001	22/54 (41%)
HB-1	NP_186796.1	HOX	66..121	CDD:197696	23/57 (40%)
HB-1	NP_186796.1	HALZ	123..165	CDD:396657	9/44 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4196
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000