DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HGTX and URAD

DIOPT Version :9

Sequence 1:NP_001368954.1 Gene:HGTX / 53446 FlyBaseID:FBgn0040318 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001099047.1 Gene:URAD / 646625 HGNCID:17785 Length:173 Species:Homo sapiens


Alignment Length:87 Identity:19/87 - (21%)
Similarity:29/87 - (33%) Gaps:30/87 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   440 ERLSNTMSANLSQSHQHHPSNDKDGKKKH------------------TRPTFSGQQI----FALE 482
            ||.....:|..||    .|.:|.:..:||                  ..|..:|.::    ...|
Human    23 ERCPLIAAAVWSQ----RPFSDLEDLEKHFFAFIDALAQSGQEGILRCHPDLAGSELQRGTLTAE 83

  Fly   483 KTFEQT----KYLAGPERAKLA 500
            ...||:    :.|...||.:||
Human    84 SQREQSGAGLRSLGADERLRLA 105

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HGTXNP_001368954.1 ROM1 179..>388 CDD:227709
Homeobox 469..523 CDD:395001 10/40 (25%)
URADNP_001099047.1 OHCU_decarbox 10..163 CDD:286439 19/87 (22%)
Substrate binding. /evidence=ECO:0000255 84..88 0/3 (0%)
Substrate binding. /evidence=ECO:0000255 119..123
Microbody targeting signal. /evidence=ECO:0000255 171..173
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0850
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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