Protein Alignment HGTX and nkx6-1

DIOPT Version :9

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001016583.2
• Gene: nkx6-1 / 549337
• XenbaseID: XB-GENE-483574
• Length: 342
• Species: Xenopus tropicalis
• Alignment Length: 359
• Identity: 151/359 - (42%)
• Similarity: 188/359 - (52%)
• Gaps: 93/359 - (25%)

  Fly   291 SFL--GPPLAALHSMTTEMK--------------GQGVGGSSASANGLSYSHSP---------NS 330
            :||  .||||||||| .|||              ......||:|::.||.|.||         :.
 Frog     8 AFLLSSPPLAALHSM-AEMKAPLYPAYTLPVQACSSSTSSSSSSSSSLSSSPSPPLGSPTQLTHK 71

  Fly   331 HLISDRGSGGSSSSSSTTTTNTNSQGAPNPHGIDTILSKP-----PPV-----TSAGLSALTG-- 383
            |..|...|||.|..:.....:     |..||||:.|||:|     |.:     :||..:|:..
 Frog    72 HSSSPPSSGGLSLGTPPLQIS-----AATPHGINDILSRPIVSCLPSLALTTSSSASSAAVASSS 131

  Fly   384 ------AGIPRFS--------------IAAAAAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGL 428
                  ||:||||              ..:||..:|:|     ..||....|    ||.::||
 Frog   132 SPAGILAGLPRFSSLSPPPPPPPGLYFSPSAAMAVARY-----PKPLTDLPG----RTPIFWP-- 185

  Fly   429 QGLVANPIAWRE-RLSNTMSANLSQSHQHHPSNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLA 492
             |::.:| .||: ||:       ...||.....|||||:||||||||||||||||||||||||||
 Frog   186 -GVMQSP-PWRDARLA-------CGPHQGSVLLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLA 241

  Fly   493 GPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQDD----MGGDNDGDCSETMDS 553
            |||||:|||:|||:|||||||||||||||||:|||||||||:|||.    :.|.:|.:  |..|.
 Frog   242 GPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDTETERLKGASDNE--EEDDD 304

  Fly   554 DNESLDMG---ESPAQNKRCRSNSSGSSQQQQDN 584
            .|:.||..   |...|..:...:||....||.:|
 Frog   305 YNKPLDPNSDDEKITQLLKKHKSSSAILLQQSEN 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	43/139 (31%)
		Homeobox	469..523	CDD:395001	50/53 (94%)
nkx6-1	NP_001016583.2	Homeobox	218..271	CDD:278475	49/52 (94%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000