Protein Alignment HGTX and MSX1

DIOPT Version :9

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_002439.2
• Gene: MSX1 / 4487
• HGNCID: 7391
• Length: 303
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 67/276 - (24%)
• Similarity: 114/276 - (41%)
• Gaps: 77/276 - (27%)

  Fly   296 PLAALHSMTTEMK------GQGVGGSSASANGLSYSHSPNSHLISDRGSGGSSSSSSTTTTNTNS 354
            |.|.:.|:...:|      |:..||.:                    |...|:::::......:.
Human     3 PAADMTSLPLGVKVEDSAFGKPAGGGA--------------------GQAPSAAAATAAAMGADE 47

  Fly   355 QGA-----PN--PHGIDTILS---KPPPVTSA-----GLSALTGA----GIPRFSIAAAAA---- 396
            :||     |:  |..::.:::   ||....||     |:.|..|:    |:|..|:.|..|
Human    48 EGAKPKVSPSLLPFSVEALMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSP 112

  Fly   397 ------GMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTMSANLSQ--- 452
                  .:...|...:.|.:|..:....:||    |.:|.         .|.|...:..||.
Human   113 RPLGHFSVGGLLKLPEDALVKAESPEKPERT----PWMQS---------PRFSPPPARRLSPPAC 164

  Fly   453 SHQHHPSNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNR 517
            :.:.|.:|.|      .|..|:..|:.|||:.|.|.:||:..|||:.:.:|.::|:|||:|||||
Human   165 TLRKHKTNRK------PRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNR 223

  Fly   518 RTKWRKRHAAEMATAK 533
            |.|.::...||:...|
Human   224 RAKAKRLQEAELEKLK 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	21/116 (18%)
		Homeobox	469..523	CDD:395001	25/53 (47%)
MSX1	NP_002439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..55		7/56 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..117		12/47 (26%)
		PTZ00449	<105..>248	CDD:185628	44/154 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..174		11/53 (21%)
		Homeobox	175..229	CDD:395001	25/53 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810