Protein Alignment HGTX and cdx1

DIOPT Version :9

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_989416.1
• Gene: cdx1 / 395055
• XenbaseID: XB-GENE-485396
• Length: 262
• Species: Xenopus tropicalis
• Alignment Length: 262
• Identity: 69/262 - (26%)
• Similarity: 99/262 - (37%)
• Gaps: 62/262 - (23%)

  Fly   323 SYSHSPNSHLISDRGSGGSSSSSSTTTTNTNSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIP 387
            ||.|.|..:.....|..|.:.||.|.     |:...:|:|       |.|    |.|:...|.|
 Frog    42 SYHHVPGINSDPHHGQPGGTWSSYTP-----SREDWHPYG-------PGP----GASSANPAQI- 89

  Fly   388 RFS------IAAAAAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTM 446
            .||      :.....|:......|..:||...|    .|.:||            .|..|.....
 Frog    90 SFSPSDYNPVQPPGPGLLPPSLNSSVSPLSPSA----QRRNLY------------EWMRRTGVPT 138

  Fly   447 SANLSQSHQHHPSNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVK 511
            |.|         ||.|...|...|..::..|...|||.|..::|:....:|:||.:|.::|.|||
 Frog   139 STN---------SNGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAASLALTERQVK 194

  Fly   512 VWFQNRRTKWRKRHAAEMATAKRKQDDMGGDNDGDCSETMDSDNESLDMGESPAQNKRCRSNSSG 576
            :||||||.|.||.:..:|....::           .|.|..:..   .:|.:......|.|:||.
 Frog   195 IWFQNRRAKERKVNKKKMQQQSQQ-----------ASTTTPTPP---SVGTTAGMGGLCSSSSSN 245

  Fly   577 SS 578
            |:
 Frog   246 SN 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	18/64 (28%)
		Homeobox	469..523	CDD:395001	22/53 (42%)
cdx1	NP_989416.1	Caudal_act	13..133	CDD:282574	29/123 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..120		24/94 (26%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	152..173		6/20 (30%)
		Homeobox	153..205	CDD:278475	22/51 (43%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	191..202		8/10 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..262		12/59 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910