DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HGTX and emx1

DIOPT Version :9

Sequence 1:	NP_001368954.1	Gene:	HGTX / 53446	FlyBaseID:	FBgn0040318	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_937787.1	Gene:	emx1 / 378964	ZFINID:	ZDB-GENE-031007-7	Length:	231	Species:	Danio rerio

Alignment Length:	208	Identity:	63/208 - (30%)
Similarity:	88/208 - (42%)	Gaps:	49/208 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 IDTILSKPPPVT-------------SAGLSALTGAGIPRFSIAAAAAGMAQY------LSQS-QG 407
            |:::::|..|:|             :...|.|.|...|        ||.|.|      .|:: ..
Zfish    12 IESLVAKESPITLEDPIRPTALSYSAPADSFLNGYQSP--------AGRALYPNPELVFSETVNH 68

  Fly   408 APLKTHAGHIVDRTHLYWPGLQG------LVANPIAWRERL------SNTMSANLSQSHQHHPSN 460
            |||..|. |.:....|..|...|      |...|...|.|.      .|.:|.:....|.....
Zfish    69 APLSMHP-HQLGSAPLQHPHFFGTQHREPLNFYPWVLRNRFFGHRFQGNDVSQDTLLLHGPFAR- 131

  Fly   461 DKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRH 525
                |.|..|..||..|:..||:.||:..|:.|.||.:||.:|.:||:||||||||||||::::.
Zfish   132 ----KPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLANSLSLSETQVKVWFQNRRTKYKRQK 192

  Fly   526 AAE---MATAKRK 535
            ..|   ..|.|:|
Zfish   193 LEEEGPECTQKKK 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	7/37 (19%)
HGTX	NP_001368954.1	Homeobox	469..523	CDD:395001	29/53 (55%)
emx1	NP_937787.1	COG5576	82..>192	CDD:227863	41/114 (36%)
		Homeobox	137..189	CDD:278475	29/51 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	193..231		4/13 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810