Protein Alignment HGTX and Nkx6-2

DIOPT Version :9

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001101028.1
• Gene: Nkx6-2 / 309095
• RGDID: 1307280
• Length: 277
• Species: Rattus norvegicus
• Alignment Length: 298
• Identity: 130/298 - (43%)
• Similarity: 158/298 - (53%)
• Gaps: 78/298 - (26%)

  Fly   284 MDHKLPLSFL--GPPLAALHSMTTEMKG-------QGVGGSSASANGLSYSHSPNSHLISDRGSG 339
            ||...|.:|:  ..||||||:| .|||.       ||..|....|                .||.
  Rat     1 MDANRPGAFVLSSAPLAALHNM-AEMKTSLFPYALQGPAGFKTPA----------------LGSL 48

  Fly   340 GSSSSSSTTTTNTNSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGM----AQ 400
            |:.....|            ||||..||.:|......||.    ..:||.:..|::||:    |.
  Rat    49 GAQLPLGT------------PHGISDILGRPVGAAGGGLL----GSLPRLNGLASSAGVYFGPAA 97

  Fly   401 YLSQSQGAPLKTHAGHIVDRTHLYWPG-LQGLVANPIAWRERLSNTMSANLSQSHQHHPSNDKDG 464
            .:::....||....|    |..::||| :||   :|  ||:       ..|:.|.|.....||||
  Rat    98 AVARGYPKPLAELPG----RPPIFWPGVVQG---SP--WRD-------PRLAGSAQAGGVLDKDG 146

  Fly   465 KKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEM 529
            ||||:||||||||||||||||||||||||||||:|||:|||:|||||||||||||||||||||||
  Rat   147 KKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEM 211

  Fly   530 ATAKRKQDDMGGDNDGDCSETMDSDNESLDMGESPAQN 567
            |:||:||               |||.|.|.:|.|.|::
  Rat   212 ASAKKKQ---------------DSDAEKLKVGGSDAED 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	31/112 (28%)
		Homeobox	469..523	CDD:395001	49/53 (92%)
Nkx6-2	NP_001101028.1	Homeobox	151..205	CDD:395001	49/53 (92%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	117	1.000	Domainoid score	I5762
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001882
OrthoInspector	1	1.000	-	-		otm46415
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24340
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.910