Protein Alignment HGTX and nkx2.5

DIOPT Version :9

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_571496.2
• Gene: nkx2.5 / 30696
• ZFINID: ZDB-GENE-980526-321
• Length: 314
• Species: Danio rerio
• Alignment Length: 294
• Identity: 71/294 - (24%)
• Similarity: 110/294 - (37%)
• Gaps: 74/294 - (25%)

  Fly   353 NSQGAPNPHGIDTILS---KPPPVTSAGLS-ALTGAGIPRFSIAAAAAGMAQYLSQSQGA----- 408
            :||....|..:..||:   ....:.|..:| .|..|.||..|...:.....|::....|:
Zfish     5 SSQMTSTPFSVRDILNLEQNQEDMVSLDMSQRLDSALIPTSSCMLSTFKQEQFMEMPSGSSLFSE 69

  Fly   409 PLKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTMSANLSQSH--------QHHPSND---- 461
            .|:...|:.::..:.   ...|..|......:.:.:..:.:..:..        |..|..|
Zfish    70 DLQEDKGNKINSINF---SASGFYAKNFLEMDYVKDAKTDDTFEDKEKKDIGCCQEDPGEDLKLD 131

  Fly   462 -----KDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKW 521
                 |..|::..|..||..|::.||:.|:|.|||:.|||..||..|.::.:|||:||||||.|.
Zfish   132 DAERPKQRKRRKPRVLFSQAQVYELERRFKQQKYLSAPERDHLANVLKLTSTQVKIWFQNRRYKC 196

  Fly   522 RKRHAAEMATAKRKQD---DMGG------------DNDG-DCSETMDSDNESLDMG--------- 561
            :          :::||   :|.|            ..|| .|.....:.|.|.::|
Zfish   197 K----------RQRQDQTLEMVGIAPPRRISVPVLVRDGKPCLGDTSTYNTSYNVGINHFTYNTY 251

  Fly   562 ------ESPA-QNKRCRSNSSGSS---QQQQDNY 585
                  .||. .|..|...||.||   .|...||
Zfish   252 PAFSNFPSPGNSNYSCNYPSSMSSIQPSQSNSNY 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	10/38 (26%)
		Homeobox	469..523	CDD:395001	27/53 (51%)
nkx2.5	NP_571496.2	Homeobox	144..197	CDD:306543	27/52 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910