Protein Alignment HGTX and Nkx2-1

DIOPT Version :9

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_006240178.1
• Gene: Nkx2-1 / 25628
• RGDID: 3866
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 415
• Identity: 104/415 - (25%)
• Similarity: 151/415 - (36%)
• Gaps: 111/415 - (26%)

  Fly   184 PPASSRLHSDSSPSPRYEHNSSP-GVDSAKSYALSQRSSGAEDPCQTSESASPPPQGQND-YSPE 246
            ||:   |||......|    |:| .|...:| |||:|...:..|..|:      |...:| .||.
  Rat    21 PPS---LHSSQLRRTR----STPLRVHPTRS-ALSRRRIMSMSPKHTT------PFSVSDILSPL 71

  Fly   247 NLSSQRAKFQHHHGVNPLALHNANHAGNPGCHNNNNHMDHKLPLSFLGPPLAALHSMTTEMKGQG 311
            ..|.::...:......|||.:....|..|......:.:.|.      |...||.|     |...|
  Rat    72 EESYKKVGMEGGGLGAPLAAYRQGQAAPPAAAMQQHAVGHH------GAVTAAYH-----MTAAG 125

  Fly   312 VGGSSASANGLSYSHSPNSHLISDRGSGGSSSSSSTTTTNTNSQGAPNPHGIDTILSKPPPVTSA 376
            |...|.||.| .|.   |.:|      |..|.......|..||...|..:|     :.|.
  Rat   126 VPQLSHSAVG-GYC---NGNL------GNVSELPPYQDTMRNSASGPGWYG-----ANPD----- 170

  Fly   377 GLSALTGAGIPRFSIAAAAAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAWRER 441
                      |||...:...|.|..::.|                     |:.||.:
  Rat   171 ----------PRFPAISRFMGPASGMNMS---------------------GMGGLGS-------- 196

  Fly   442 LSNTMSANLSQSHQHHPSNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMS 506
                 ..::|::....||    ..::..|..||..|::.||:.|:|.|||:.|||..||..:.::
  Rat   197 -----LGDVSKNMAPLPS----APRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLT 252

  Fly   507 ESQVKVWFQNRRTKWRKRHAAEMATAKRKQDDMGGDNDG----DCSETMDSDNESLDMGESPA-- 565
            .:|||:||||.|.| .||.|.:.|..::.|.|.||...|    .|.:...:..:|......|.
  Rat   253 PTQVKIWFQNHRYK-MKRQAKDKAAQQQLQQDSGGGGGGGGGAGCPQQQQAQQQSPRRVAVPVLV 316

  Fly   566 -QNKRCRSNS--------SGSSQQQ 581
             ..|.|::.:        .|.:|||
  Rat   317 KDGKPCQAGAPAPGAASLQGHAQQQ 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	49/205 (24%)
		Homeobox	469..523	CDD:395001	25/53 (47%)
Nkx2-1	XP_006240178.1	Homeobox	215..268	CDD:278475	25/53 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000