DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HGTX and Obox5

DIOPT Version :9

Sequence 1:	NP_001368954.1	Gene:	HGTX / 53446	FlyBaseID:	FBgn0040318	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_663755.2	Gene:	Obox5 / 252829	MGIID:	2149035	Length:	291	Species:	Mus musculus

Alignment Length:	205	Identity:	48/205 - (23%)
Similarity:	83/205 - (40%)	Gaps:	46/205 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 AAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPG--LQGLVANPIAWRERLSNTMSANLSQSHQHH 457
            |..:|..:|||   ||.|             ||  :|..::.|   ...|....|...|:.....
Mouse    30 ARNLAFQMSQS---PLVT-------------PGSTMQSSLSVP---ERNLLQQESEGSSRQSGSM 75

  Fly   458 PSNDK----------DGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKV 512
            |.:||          ..|.:..|..::.:|...|:|.|::.:|....:..:||.::|:::.::|:
Mouse    76 PLSDKYVNKQTGPMASRKFRKERTVYTKEQQRLLQKHFDECQYPNEKKIMELAVSVGVTKMEIKI 140

  Fly   513 WFQNRRTKWRKRHAAEMATAKRKQDDMGGDNDGDCSET--------MDSDN-ESL---DMGESPA 565
            ||:|.|.|:|:.:   :...|:...:..|.:......|        :.||| ||:   ..||...
Mouse   141 WFKNNRAKYRRMN---LQNIKQALPESNGISKAVSESTHFPGSIPVVASDNGESMCSGTFGEDSM 202

  Fly   566 QNKRCRSNSS 575
            ....|...||
Mouse   203 PKFNCSQESS 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709
HGTX	NP_001368954.1	Homeobox	469..523	CDD:395001	15/53 (28%)
Obox5	NP_663755.2	homeodomain	95..153	CDD:238039	16/57 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810