Protein Alignment HGTX and Tlx2

DIOPT Version :9

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_033418.1
• Gene: Tlx2 / 21909
• MGIID: 1350935
• Length: 284
• Species: Mus musculus
• Alignment Length: 278
• Identity: 84/278 - (30%)
• Similarity: 111/278 - (39%)
• Gaps: 87/278 - (31%)

  Fly   282 NHMDHKLPLSF------LGPPLAALHSMTTEMKGQGVG-GSSASANGLSYSHSPNSHLISDRGSG 339
            :|:.|..|:||      .||          |..|.|:| |.|..::|.|.:.|...|     |:.
Mouse     9 HHLPHHEPISFGIDQILSGP----------EPPGGGLGPGQSGQSHGESAAFSSGFH-----GAS 58

  Fly   340 GSSSSSSTTTTNTNSQGAPNPHGIDTI-----LSKPPPVTSA----GLSALTGAGIPRFSIAAAA 395
            |.:.:.|..:....|  ...|.|:..:     |..|||..:|    |.|.|.|||
Mouse    59 GYAPAGSLASLPRGS--GVGPGGVIRVPAHRPLPVPPPSGAAPAVPGPSGLGGAG---------- 111

  Fly   396 AGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAW--------RERLSNTMSANLSQ 452
                                           ||.||.   ..|        ::||:..:|.....
Mouse   112 -------------------------------GLAGLT---FPWMDSGRRFAKDRLTAALSPFSGT 142

  Fly   453 SHQHHP-SNDKDGKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQN 516
            ....|| .|....|:|..|.:||..|:..||:.|.:.||||..|||.||.||.|:::|||.||||
Mouse   143 RRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQN 207

  Fly   517 RRTKWRKRHAAEMATAKR 534
            |||||| |..||...|:|
Mouse   208 RRTKWR-RQTAEEREAER 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	34/121 (28%)
		Homeobox	469..523	CDD:395001	31/53 (58%)
Tlx2	NP_033418.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..52		10/41 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..104		6/25 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..166		7/25 (28%)
		Homeobox	160..213	CDD:306543	30/52 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870