Protein Alignment HGTX and Nkx1-2

DIOPT Version :9

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_033149.1
• Gene: Nkx1-2 / 20231
• MGIID: 104806
• Length: 305
• Species: Mus musculus
• Alignment Length: 255
• Identity: 65/255 - (25%)
• Similarity: 100/255 - (39%)
• Gaps: 70/255 - (27%)

  Fly   286 HKLPLSFLG------------PP--LAALHSMTTEMKGQGVGGSSASANGLSYSHSPNSHLISDR 336
            ||:..|.|.            ||  ||||.:..: ::....|..:.|.|.:....:|::   ..|
Mouse    16 HKISFSVLDILDPQKFTRAALPPVRLAALEAKKS-LEEVEAGQDACSGNPIGSQETPDA---VGR 76

  Fly   337 G-SGGSSSSSSTTTTNTNSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGMAQ 400
            | ..||....|.......::.|...|       :|.          ...|:...|..|.|..:..
Mouse    77 GIDPGSPVEGSEAEEEEEAEDAGRAH-------QPE----------RWQGVHEGSPEARAVAVGT 124

  Fly   401 YLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHHPSNDKDGK 465
            ..|.::|.|..              ||..|   :|...|.|..::.:                 |
Mouse   125 EESGAEGLPAS--------------PGSPG---SPRPRRRRAESSCA-----------------K 155

  Fly   466 KKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRH 525
            .:..|..|:.:|:.|||..|..|:||:..||..||.:|.::|:|||:|||||||||:|::
Mouse   156 PRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQN 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	23/116 (20%)
		Homeobox	469..523	CDD:395001	28/53 (53%)
Nkx1-2	NP_033149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..158		26/160 (16%)
		Homeobox	160..212	CDD:278475	27/51 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..257		3/6 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910