Protein Alignment HGTX and EMX1

DIOPT Version :10

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 71/236 - (30%)
• Similarity: 98/236 - (41%)
• Gaps: 65/236 - (27%)

  Fly   330 SHLISDRGSGGSSSSSSTTTTNTNSQGAPNPHGIDTILSKPP--------PVTSAGLSALTGAGI 386
            |.:..|.|:||.:..           |....|.:....|:.|        |..||..:|.. :|.
Human    47 SLVAKDGGTGGGTGG-----------GGAGSHLLAAAASEEPLRPTALNYPHPSAAEAAFV-SGF 99

  Fly   387 PRFSIAAAAAGMAQYLSQSQGAP------------LKTHAGHIVDRTHLYWP----GLQGLVANP 435
            |    ||||||..:.|   .|.|            |..|..|.:..:.|..|    |.|.  .:|
Human   100 P----AAAAAGAGRSL---YGGPELVFPEAMNHPALTVHPAHQLGASPLQPPHSFFGAQH--RDP 155

  Fly   436 I---AWRERLSNTMSANLSQSHQHHPSN-DKDG---------KKKHTRPTFSGQQIFALEKTFEQ 487
            :   .|..|       |....|:...|: .:||         |.|..|..||..|:..||:.||:
Human   156 LHFYPWVLR-------NRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEK 213

  Fly   488 TKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAE 528
            ..|:.|.||.:||.:|.:||:||||||||||||::::...|
Human   214 NHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEE 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	14/65 (22%)
		Homeodomain	465..523	CDD:459649	31/57 (54%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		1/6 (17%)