DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HGTX and vab-15

DIOPT Version :9

Sequence 1:	NP_001368954.1	Gene:	HGTX / 53446	FlyBaseID:	FBgn0040318	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_509648.1	Gene:	vab-15 / 181197	WormBaseID:	WBGene00006881	Length:	225	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	57/208 - (27%)
Similarity:	89/208 - (42%)	Gaps:	55/208 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   367 LSKPPPVTS------AGLSALT---GAGIPRFSIAAAAAGMAQYLSQSQGAPLKTHAGHIVDRTH 422
            |.||.|:|.      .||..:|   ||.:....|..|..|....:..|..:|
Worm    31 LPKPTPITPKTPMLIPGLHPMTPYFGAQLDPVMIYFAQTGNRLPIVSSDSSP------------- 82

  Fly   423 LYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHHPSNDKDGK----------KKH-----TRPT 472
                  :...::|::.:..|.     .||...:..|::| |.|          :||     .|..
Worm    83 ------ESCASSPLSMQHSLQ-----WLSSQREDSPTSD-DAKIQIGLSKCMLRKHKNNRKPRTP 135

  Fly   473 FSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQD 537
            ||.||:.:||:.|:..:||:..|||:.:.:|.::|:|||:||||||.|.::...||:...|..|.
Worm   136 FSTQQLISLERKFQSKQYLSIAERAEFSASLQLTETQVKIWFQNRRAKSKRLQEAEVEKVKFAQA 200

  Fly   538 D------MGGDND 544
            .      :||..|
Worm   201 SAYAAAAVGGAPD 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	10/29 (34%)
HGTX	NP_001368954.1	Homeobox	469..523	CDD:395001	25/53 (47%)
vab-15	NP_509648.1	Homeobox	132..185	CDD:278475	25/52 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810