DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HGTX and Nkx2-9

DIOPT Version :9

Sequence 1:	NP_001368954.1	Gene:	HGTX / 53446	FlyBaseID:	FBgn0040318	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_032727.2	Gene:	Nkx2-9 / 18094	MGIID:	1270158	Length:	235	Species:	Mus musculus

Alignment Length:	130	Identity:	40/130 - (30%)
Similarity:	60/130 - (46%)	Gaps:	19/130 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   429 QGLVANPIAWRE--------------RLSNTMSANLSQSHQHHPSNDKDGKKKHTRPTFSGQQIF 479
            |..|....||.|              ..|...|:.|:...:..|.:|.: |::..|..||..|..
Mouse    31 QTCVPQTAAWLESECSHYLSSDESGLETSPADSSQLASLRRESPGSDPE-KRRKRRVLFSKAQTL 94

  Fly   480 ALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQDDMGGDND 544
            .||:.|.|.:||:.|||.:||..|.::.:|||:||||.|.|.::..|..:.    :..||...:|
Mouse    95 ELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGRAPGIT----EPSDMAASSD 155

Fly 545 544
Mouse 156 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709
HGTX	NP_001368954.1	Homeobox	469..523	CDD:395001	25/53 (47%)
Nkx2-9	NP_032727.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..86		6/35 (17%)
Nkx2-9	NP_032727.2	Homeobox	84..138	CDD:365835	25/53 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833335
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930