Protein Alignment HGTX and Nkx2-2

DIOPT Version :9

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_035049.1
• Gene: Nkx2-2 / 18088
• MGIID: 97347
• Length: 273
• Species: Mus musculus
• Alignment Length: 204
• Identity: 60/204 - (29%)
• Similarity: 85/204 - (41%)
• Gaps: 40/204 - (19%)

  Fly   346 STTTTNTNSQ-----GAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGMAQYLSQS 405
            |.|.|.|...     ..|:.:..|..:::.|...|.|         |..:..|...|... |...
Mouse     2 SLTNTKTGFSVKDILDLPDTNDEDGSVAEGPEEESEG---------PEPAKRAGPLGQGA-LDAV 56

  Fly   406 QGAPLKTHAGHIVDRTHLYW----PGLQ----GLVAN--PIAWRERLSNTMSANLSQSHQHHPSN 460
            |..|||:......|..:..|    .|||    ||.|:  |       .::.|.:...|....|.|
Mouse    57 QSLPLKSPFYDSSDNPYTRWLASTEGLQYSLHGLAASAPP-------QDSSSKSPEPSADESPDN 114

  Fly   461 DKD--------GKKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNR 517
            ||:        |||:..|..||..|.:.||:.|.|.:||:.|||..||..:.::.:|||:||||.
Mouse   115 DKETQGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNH 179

  Fly   518 RTKWRKRHA 526
            |.|.::..|
Mouse   180 RYKMKRARA 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	9/46 (20%)
		Homeobox	469..523	CDD:395001	24/53 (45%)
Nkx2-2	NP_035049.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		13/63 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..131		11/46 (24%)
		Homeobox	131..185	CDD:395001	24/53 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910