Protein Alignment HGTX and Nkx3-2

DIOPT Version :9

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_031550.2
• Gene: Nkx3-2 / 12020
• MGIID: 108015
• Length: 333
• Species: Mus musculus
• Alignment Length: 390
• Identity: 95/390 - (24%)
• Similarity: 134/390 - (34%)
• Gaps: 144/390 - (36%)

  Fly   163 MLLKAAHGGGLKDSDSPSTTPPPASSRLHSDSSPSP---RYEHNSSPGVDSAKSYALSQRSSGAE 224
            :|.|....|||.   :|...|.|..:.:...::|:.   |....:..|       ||    .|||
Mouse    17 ILNKKEERGGLA---TPEGRPAPGGTEVAVTAAPAVCCWRIFGETEAG-------AL----GGAE 67

  Fly   225 DPCQTSESASPPPQGQNDYSPENLSSQRAKFQHHHGVNPLA-LHNANHAG---------NPGCHN 279
            |....|.:.:....||:..||....|..|..:.:.|....| :..|:..|         .|||.
Mouse    68 DSLLASPARTRTAVGQSAESPGGWDSDSALSEENEGRRRCADVPGASGTGRARVTLGLDQPGCE- 131

  Fly   280 NNNHMDHKLPLSFLGPPLAALHSMTTEMKGQGVGGSSASANGLSYSHSPNSHLISDRGSGGSSSS 344
                             |.|...:..|...:.....|||.:|   .|||       ||...|.|.
Mouse   132 -----------------LHAAKDLEEEAPVRSDSEMSASVSG---DHSP-------RGEDDSVSP 169

  Fly   345 SSTTTTNTNSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGMAQYLSQSQGAP 409
            .          ||..|                ||....|:|        |:.|.|..:.:.:
Mouse   170 G----------GARVP----------------GLRGAAGSG--------ASGGQAGGVEEEE--- 197

  Fly   410 LKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHHPSNDKDGKKKHTRPTFS 474
                                    .|.|.:.|                        ||.:|..||
Mouse   198 ------------------------EPAAPKPR------------------------KKRSRAAFS 214

  Fly   475 GQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRH-AAEM---ATAKRK 535
            ..|:|.||:.|...:||:|||||.||.:|.::|:|||:||||||.|.::|. ||::   |.|.:|
Mouse   215 HAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKK 279

  Fly   536  535
            Mouse   280  279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	47/221 (21%)
		Homeobox	469..523	CDD:395001	29/53 (55%)
Nkx3-2	NP_031550.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	74..121		10/46 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..212		28/169 (17%)
		Homeobox	209..262	CDD:278475	29/52 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910