Protein Alignment HGTX and tlx1

DIOPT Version :10

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_002936814.1
• Gene: tlx1 / 100494864
• XenbaseID: XB-GENE-485834
• Length: 311
• Species: Xenopus tropicalis
• Alignment Length: 313
• Identity: 87/313 - (27%)
• Similarity: 113/313 - (36%)
• Gaps: 118/313 - (37%)

  Fly   276 GCHNNNNHMDHKLPLSF----------------LGPPL------------AALHSMTTEMKGQGV 312
            |.|  :.|..|..|:||                .||.|            :|.::||......|.
 Frog     5 GAH--HIHQTHAEPISFGIDQILNNPDQGSCMISGPRLQDSDYGLGCIVSSAYNTMTGNYSNSGT 67

  Fly   313 GGSSASANGLSYSHSPNSHLISDRGSGGSSSSSSTTTTNTNSQG---APNPHGIDTILSKP---- 370
            ||.|.||..::          |..||...:...:....|.||.|   .|....:.|.:.:|
 Frog    68 GGYSNSACSMA----------SLTGSYNMNMGVTMNGNNLNSAGVIRVPAHRPLATSVHQPISTG 122

  Fly   371 -PPVTSAG----LSALTGAGIP-----------RFSIAAAAAGMAQYLSQSQGAPLKTHAGHIVD 419
             |.|.|.|    ::.|||...|           ||::|
 Frog   123 MPTVPSVGSMNNMNNLTGLTFPWMESNRRYTKDRFTVA--------------------------- 160

  Fly   420 RTHLYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHHP-SNDKDGKKKHTRPTFSGQQIFALEK 483
                         .:|.....|:.             || .|....|||..|.:|:..||..|||
 Frog   161 -------------LSPFTVTRRIG-------------HPYQNRTPPKKKKPRTSFTRLQICELEK 199

  Fly   484 TFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQ 536
            .|.:.||||..|||.||.||.|:::|||.|||||||||| |..||...|:|:|
 Frog   200 RFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWR-RQTAEEREAERQQ 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	37/162 (23%)
		Homeodomain	465..523	CDD:459649	35/57 (61%)
tlx1	XP_002936814.1	Homeodomain	183..239	CDD:459649	34/56 (61%)