Protein Alignment HGTX and hlx

DIOPT Version :10

• Sequence 1: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_004914850.1
• Gene: hlx / 100488508
• XenbaseID: XB-GENE-483226
• Length: 397
• Species: Xenopus tropicalis
• Alignment Length: 309
• Identity: 56/309 - (18%)
• Similarity: 99/309 - (32%)
• Gaps: 93/309 - (30%)

  Fly   584 QKTFQEETNKQPEGYNEKIMETGK-----------------KINEDGTRKVQEMIRQQE------ 625
            |..|.|....|.|....|.:..|:                 |:...|.:.:|..:||.|
 Frog    71 QLNFIENPVSQVEILKNKPLSVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTEDYPVDL 135

  Fly   626 ---------LDEPARSEKE---NRSRELVKSKTNDE-------EKKEKEIAGTERKE-------- 663
                     :|:...:.||   ..|:|:.|..:|..       ||.......|..:|
 Frog   136 YYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSI 200

  Fly   664 -----------------KESDR-PKILREQEVADEVAEDKTKFSIYGEVKEEEE----------- 699
                             .:::| .:|::.|:::..:...:..|....:....:|
 Frog   201 PYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHL 265

  Fly   700 ---IAGKEKEFGSDDDIARIVRDTE---QLDSN---AMKGQEEKDMIQELVLEEKVCDGGKGIIA 755
               ::..:..||.|..:|.||...:   .|||.   :|....|...|.:|: ::.|.:....|.|
 Frog   266 LVFVSDADSHFGMDSKLAGIVIPNDGLCHLDSKNEYSMSTVLEYPTIGQLI-DKLVQNNVLLIFA 329

  Fly   756 VAETKAE--NNKSKRVQETEEQKLDKEDTCGKHFQKLIEGEISDHGEVE 802
            |.:.:..  .|.:|.:.......|.|:.  |...|.:|........|||
 Frog   330 VTQEQVHLYENYAKLIPGATVGLLQKDS--GNILQLIISAYEELRSEVE 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709
		Homeodomain	465..523	CDD:459649
hlx	XP_004914850.1	Homeodomain	244..304	CDD:459649	10/59 (17%)